The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

Y. L. Matory, A. E. Chang, E. H. Lipford, Rita Braziel, C. L. Hyatt, S. A. Rosenberg

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.

Original languageEnglish (US)
Pages (from-to)537-541
Number of pages5
JournalJournal of the National Medical Association
Volume79
Issue number5
StatePublished - 1987
Externally publishedYes

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Intravenous Infusions
Interleukin-2
Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Matory, Y. L., Chang, A. E., Lipford, E. H., Braziel, R., Hyatt, C. L., & Rosenberg, S. A. (1987). The toxicity of recombinant human interleukin-2 in rats following intravenous infusion. Journal of the National Medical Association, 79(5), 537-541.

The toxicity of recombinant human interleukin-2 in rats following intravenous infusion. / Matory, Y. L.; Chang, A. E.; Lipford, E. H.; Braziel, Rita; Hyatt, C. L.; Rosenberg, S. A.

In: Journal of the National Medical Association, Vol. 79, No. 5, 1987, p. 537-541.

Research output: Contribution to journalArticle

Matory, YL, Chang, AE, Lipford, EH, Braziel, R, Hyatt, CL & Rosenberg, SA 1987, 'The toxicity of recombinant human interleukin-2 in rats following intravenous infusion', Journal of the National Medical Association, vol. 79, no. 5, pp. 537-541.
Matory, Y. L. ; Chang, A. E. ; Lipford, E. H. ; Braziel, Rita ; Hyatt, C. L. ; Rosenberg, S. A. / The toxicity of recombinant human interleukin-2 in rats following intravenous infusion. In: Journal of the National Medical Association. 1987 ; Vol. 79, No. 5. pp. 537-541.
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