The Symptom Experience in Rectal Cancer Survivors

Tracy K. Gosselin, Susan Beck, David H. Abbott, Steven C. Grambow, Dawn Provenzale, Patricia Berry, Katherine L. Kahn, Jennifer L. Malin

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    Context As the number of rectal cancer survivors grows, it is important to understand the symptom experience after treatment. Although data show that rectal cancer survivors experience a variety of symptoms after diagnosis, little has been done to study the way these symptoms are grouped and associated. Objectives To determine symptom prevalence and intensity in rectal cancer survivors and if clusters of survivors exist, who share similar symptom-defined survivor subgroups that may vary based on antecedent variables. Methods A secondary analysis of the Cancer Care and Outcomes Research and Surveillance database was undertaken. Cluster analysis was performed on 15-month postdiagnosis data to form post-treatment survivor subgroups, and these were examined for differences in demographic and clinical characteristics. Data were analyzed using cluster analysis, chi-square, and analysis of variance. Results A total of 275 rectal cancer survivors were included who had undergone chemotherapy, radiation therapy, and surgery. Most frequently reported symptoms included feeling “worn out” (87%), feeling “tired” (85%), and “trouble sleeping” (66%). Four symptom-defined survivor subgroups (minimally symptomatic n = 40, tired and trouble sleeping n = 138, moderate symptoms n = 42, and highly symptomatic n = 55) were identified with symptom differences existing among each subgroup. Age and being married/partnered were the only two antecedents found to differ across subgroups. Conclusion This study documents differences in the symptom experience after treatment. The identification of survivor subgroups allows researchers to further investigate tailored, supportive care strategies to minimize ongoing symptoms in those with the greatest symptom burden.

    Original languageEnglish (US)
    Pages (from-to)709-718
    Number of pages10
    JournalJournal of Pain and Symptom Management
    Volume52
    Issue number5
    DOIs
    StatePublished - Nov 1 2016

    Fingerprint

    Rectal Neoplasms
    Survivors
    Cluster Analysis
    Emotions
    Analysis of Variance
    Radiotherapy
    Therapeutics
    Research Personnel
    Demography
    Outcome Assessment (Health Care)
    Databases
    Drug Therapy

    Keywords

    • cluster analysis
    • Rectal cancer
    • subgroups
    • survivors
    • symptoms

    ASJC Scopus subject areas

    • Nursing(all)
    • Clinical Neurology
    • Anesthesiology and Pain Medicine

    Cite this

    Gosselin, T. K., Beck, S., Abbott, D. H., Grambow, S. C., Provenzale, D., Berry, P., ... Malin, J. L. (2016). The Symptom Experience in Rectal Cancer Survivors. Journal of Pain and Symptom Management, 52(5), 709-718. https://doi.org/10.1016/j.jpainsymman.2016.05.027

    The Symptom Experience in Rectal Cancer Survivors. / Gosselin, Tracy K.; Beck, Susan; Abbott, David H.; Grambow, Steven C.; Provenzale, Dawn; Berry, Patricia; Kahn, Katherine L.; Malin, Jennifer L.

    In: Journal of Pain and Symptom Management, Vol. 52, No. 5, 01.11.2016, p. 709-718.

    Research output: Contribution to journalArticle

    Gosselin, TK, Beck, S, Abbott, DH, Grambow, SC, Provenzale, D, Berry, P, Kahn, KL & Malin, JL 2016, 'The Symptom Experience in Rectal Cancer Survivors', Journal of Pain and Symptom Management, vol. 52, no. 5, pp. 709-718. https://doi.org/10.1016/j.jpainsymman.2016.05.027
    Gosselin, Tracy K. ; Beck, Susan ; Abbott, David H. ; Grambow, Steven C. ; Provenzale, Dawn ; Berry, Patricia ; Kahn, Katherine L. ; Malin, Jennifer L. / The Symptom Experience in Rectal Cancer Survivors. In: Journal of Pain and Symptom Management. 2016 ; Vol. 52, No. 5. pp. 709-718.
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    abstract = "Context As the number of rectal cancer survivors grows, it is important to understand the symptom experience after treatment. Although data show that rectal cancer survivors experience a variety of symptoms after diagnosis, little has been done to study the way these symptoms are grouped and associated. Objectives To determine symptom prevalence and intensity in rectal cancer survivors and if clusters of survivors exist, who share similar symptom-defined survivor subgroups that may vary based on antecedent variables. Methods A secondary analysis of the Cancer Care and Outcomes Research and Surveillance database was undertaken. Cluster analysis was performed on 15-month postdiagnosis data to form post-treatment survivor subgroups, and these were examined for differences in demographic and clinical characteristics. Data were analyzed using cluster analysis, chi-square, and analysis of variance. Results A total of 275 rectal cancer survivors were included who had undergone chemotherapy, radiation therapy, and surgery. Most frequently reported symptoms included feeling “worn out” (87{\%}), feeling “tired” (85{\%}), and “trouble sleeping” (66{\%}). Four symptom-defined survivor subgroups (minimally symptomatic n = 40, tired and trouble sleeping n = 138, moderate symptoms n = 42, and highly symptomatic n = 55) were identified with symptom differences existing among each subgroup. Age and being married/partnered were the only two antecedents found to differ across subgroups. Conclusion This study documents differences in the symptom experience after treatment. The identification of survivor subgroups allows researchers to further investigate tailored, supportive care strategies to minimize ongoing symptoms in those with the greatest symptom burden.",
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