The role of stem cells in cutaneous wound healing: What do we really know?

Sae Hee Ko, Allison Nauta, Victor Wong, Jason Glotzbach, Geoffrey C. Gurtner, Michael T. Longaker

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

Wound repair is a complex process involving the orchestrated interaction of multiple growth factors, cytokines, chemokines, and cell types. Dysregulation of this process leads to problems such as excessive healing in the form of keloids and hypertrophic scars and chronic, nonhealing wounds. These issues have broad global implications. Stem cells offer enormous potential for enhancing tissue repair and regeneration following injury. The rapidly developing fields of stem cell biology and skin tissue engineering create translational opportunities for the development of novel stem cell-based wound-healing therapies.

Original languageEnglish (US)
Pages (from-to)10S-20S
JournalPlastic and reconstructive surgery
Volume127
Issue numberSUPPL. 1 S
DOIs
StatePublished - Jan 2011
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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