TY - JOUR
T1 - The role of stem cells in cutaneous wound healing
T2 - What do we really know?
AU - Ko, Sae Hee
AU - Nauta, Allison
AU - Wong, Victor
AU - Glotzbach, Jason
AU - Gurtner, Geoffrey C.
AU - Longaker, Michael T.
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011/1
Y1 - 2011/1
N2 - Wound repair is a complex process involving the orchestrated interaction of multiple growth factors, cytokines, chemokines, and cell types. Dysregulation of this process leads to problems such as excessive healing in the form of keloids and hypertrophic scars and chronic, nonhealing wounds. These issues have broad global implications. Stem cells offer enormous potential for enhancing tissue repair and regeneration following injury. The rapidly developing fields of stem cell biology and skin tissue engineering create translational opportunities for the development of novel stem cell-based wound-healing therapies.
AB - Wound repair is a complex process involving the orchestrated interaction of multiple growth factors, cytokines, chemokines, and cell types. Dysregulation of this process leads to problems such as excessive healing in the form of keloids and hypertrophic scars and chronic, nonhealing wounds. These issues have broad global implications. Stem cells offer enormous potential for enhancing tissue repair and regeneration following injury. The rapidly developing fields of stem cell biology and skin tissue engineering create translational opportunities for the development of novel stem cell-based wound-healing therapies.
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U2 - 10.1097/PRS.0b013e3181fbe2d8
DO - 10.1097/PRS.0b013e3181fbe2d8
M3 - Article
C2 - 21200267
AN - SCOPUS:78651282162
SN - 0032-1052
VL - 127
SP - 10S-20S
JO - Plastic and reconstructive surgery
JF - Plastic and reconstructive surgery
IS - SUPPL. 1 S
ER -