The primate uterus: Cyclic changes

O. V.Daniel Slayden, Andrea Calhoun

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    Herein we describe the events involved in hormonal regulation of the primate uterus. At the onset of each menstrual cycle the luminal portion of the uterine lining, the endometrium, is sloughed during menstruation and then regenerated in the follicular phase of the cycle. In the luteal phase, the endometrium is transformed into four distinct zones characterized by the degree of glandular sacculation, steroid receptor expression, cell proliferation, and vascularization. Progesterone drives endometrial secretory differentiation. In the absence of embryo implantation, the decline in progesterone at the end of the cycle leads to menstruation and the start of a new cycle.

    Original languageEnglish (US)
    Title of host publicationEncyclopedia of Reproduction
    PublisherElsevier
    Pages312-319
    Number of pages8
    ISBN (Electronic)9780128151457
    DOIs
    StatePublished - Jan 1 2018

    Keywords

    • Cell proliferation
    • Endometrium
    • Histology
    • Macaque
    • Menstruation menstrual cycle
    • Myometrium
    • Nonhuman primates
    • Secretory differentiation
    • Uterus

    ASJC Scopus subject areas

    • Medicine(all)

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