The neurobiology of adolescence: Changes in brain architecture, functional dynamics, and behavioral tendencies

David A. Sturman; Bita Moghaddam

doi:10.1016/j.neubiorev.2011.04.003

The neurobiology of adolescence: Changes in brain architecture, functional dynamics, and behavioral tendencies

David A. Sturman, Bita Moghaddam

Research output: Contribution to journal › Review article › peer-review

212 Scopus citations

Abstract

Adolescence is a period of increased behavioral and psychiatric vulnerabilities. It is also a time of dramatic structural and functional neurodevelopment. In recent years studies have examined the precise nature of these brain and behavioral changes, and several hypotheses link them together. In this review we discuss this research and recent electrophysiological data from behaving rats that demonstrate reduced neuronal coordination and processing efficiency in adolescents. A more comprehensive understanding of these processes will further our knowledge of adolescent behavioral vulnerabilities and the pathophysiology of mental illnesses that manifest during this period.

Original language	English (US)
Pages (from-to)	1704-1712
Number of pages	9
Journal	Neuroscience and Biobehavioral Reviews
Volume	35
Issue number	8
DOIs	https://doi.org/10.1016/j.neubiorev.2011.04.003
State	Published - Aug 2011
Externally published	Yes

Keywords

Addiction
DTI
Depression
Dopamine
EEG
ERP
Electrophysiology
FMRI
Puberty
Schizophrenia

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Cognitive Neuroscience
Behavioral Neuroscience

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10.1016/j.neubiorev.2011.04.003

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abstract = "Adolescence is a period of increased behavioral and psychiatric vulnerabilities. It is also a time of dramatic structural and functional neurodevelopment. In recent years studies have examined the precise nature of these brain and behavioral changes, and several hypotheses link them together. In this review we discuss this research and recent electrophysiological data from behaving rats that demonstrate reduced neuronal coordination and processing efficiency in adolescents. A more comprehensive understanding of these processes will further our knowledge of adolescent behavioral vulnerabilities and the pathophysiology of mental illnesses that manifest during this period.",

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AB - Adolescence is a period of increased behavioral and psychiatric vulnerabilities. It is also a time of dramatic structural and functional neurodevelopment. In recent years studies have examined the precise nature of these brain and behavioral changes, and several hypotheses link them together. In this review we discuss this research and recent electrophysiological data from behaving rats that demonstrate reduced neuronal coordination and processing efficiency in adolescents. A more comprehensive understanding of these processes will further our knowledge of adolescent behavioral vulnerabilities and the pathophysiology of mental illnesses that manifest during this period.

KW - Addiction

KW - DTI

KW - Depression

KW - Dopamine

KW - EEG

KW - ERP

KW - Electrophysiology

KW - FMRI

KW - Puberty

KW - Schizophrenia

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The neurobiology of adolescence: Changes in brain architecture, functional dynamics, and behavioral tendencies

Abstract

Keywords

ASJC Scopus subject areas

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