@article{3b880b72abc842e99442cf514db31c4e,
title = "The nephropathy of the nail-patella syndrome. Clinicopathologic analysis of 11 kindred",
abstract = "Seventy-two members of 11 kindred with the nail-patella syndrome were studied. Twelve patients who had electron microscopic examinations of renal tissue had abnormalities of the glomerular basement membrane. An unaffected family member did not. This lesion consisted of irregular basement membrane thickening, epithelial foot process fusion and the presence of fibrillar collagen-like material within the substance of the membrane. Many patients also showed areas of increased lucency giving the membrane a {"}moth-eaten{"} appearance. The presence of the ultrastructural lesion bore no relation to the presence or absence of abnormalities by light or immunofluorescent microscopy and also no relation to demonstrable alterations of renal function. The determinants of clinically significant nephropathy are unknown but in most patients the prognosis is favorable.",
author = "Bennett, {William M.} and Musgrave, {James E.} and Campbell, {Robert A.} and Diane Elliot and Robert Cox and Brooks, {Robert E.} and Lovrien, {Everett W.} and Beals, {Rodney K.} and Porter, {George A.}",
note = "Funding Information: From the Departments of Medicine, Pediatrics, Orthopedics and Pathology, University of Oregon Medical School, Portland, Oregon. This investigation was supported in part by a grant RR-34 from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health. Requests for reprints should be addressed to Dr. William M. Bennett, Department of Medicine, University of Oregon Medical School, Portland, Oregon 97201. Manuscript received September 5, 1972; revision accepted November 3.1972. *Summer Fellow of the Oregon Heart Association. Present address: Washington University School of Medicine, St. Louis, Missouri 63110. tPresent address: Letterman General Hospital, San Francisco, California 94129.",
year = "1973",
month = mar,
doi = "10.1016/0002-9343(73)90025-9",
language = "English (US)",
volume = "54",
pages = "304--319",
journal = "American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "3",
}