Abstract
Fanconi anemia is a genetic instability syndrome characterized by bone marrow failure and high relative risks of myelodysplasia and acute myelogenous leukemia. Eleven of the genes and gene products have been identified, and their role in protecting the genome is being intensively investigated. The roles of these proteins in hematopoietic regulation are less broadly studied but likely involve separate biochemical functions.
Original language | English (US) |
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Pages (from-to) | 4196-4197 |
Number of pages | 2 |
Journal | Blood |
Volume | 107 |
Issue number | 11 |
DOIs | |
State | Published - Jun 1 2006 |
ASJC Scopus subject areas
- Biochemistry
- Immunology
- Hematology
- Cell Biology