Abstract
Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as highlighted in this review. An overview of how SFKs interact with, and participate in signaling from, receptor tyrosine kinases (RTKs) is discussed. And also, how SFKs are activated by RTKs, and how SFKs, in turn, can activate RTKs, as well as how SFKs can promote signaling from growth factor receptors in a number of ways including participation in signaling pathways required for DNA synthesis, control of receptor turnover, actin cytoskeleton rearrangements and motility, and survival are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 7957-7968 |
| Number of pages | 12 |
| Journal | Oncogene |
| Volume | 23 |
| Issue number | 48 REV. ISS. 7 |
| DOIs | |
| State | Published - Oct 18 2004 |
| Externally published | Yes |
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Keywords
- Mitogenesis
- Phosphotyrosine
- Src
- Survival
- Ubiquitination
ASJC Scopus subject areas
- Molecular Biology
- Cancer Research
- Genetics
Cite this
The interplay between Src family kinases and receptor tyrosine kinases. / Bromann, Paul A.; Korkaya, Hasan; Courtneidge, Sara.
In: Oncogene, Vol. 23, No. 48 REV. ISS. 7, 18.10.2004, p. 7957-7968.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The interplay between Src family kinases and receptor tyrosine kinases
AU - Bromann, Paul A.
AU - Korkaya, Hasan
AU - Courtneidge, Sara
PY - 2004/10/18
Y1 - 2004/10/18
N2 - Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as highlighted in this review. An overview of how SFKs interact with, and participate in signaling from, receptor tyrosine kinases (RTKs) is discussed. And also, how SFKs are activated by RTKs, and how SFKs, in turn, can activate RTKs, as well as how SFKs can promote signaling from growth factor receptors in a number of ways including participation in signaling pathways required for DNA synthesis, control of receptor turnover, actin cytoskeleton rearrangements and motility, and survival are discussed.
AB - Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as highlighted in this review. An overview of how SFKs interact with, and participate in signaling from, receptor tyrosine kinases (RTKs) is discussed. And also, how SFKs are activated by RTKs, and how SFKs, in turn, can activate RTKs, as well as how SFKs can promote signaling from growth factor receptors in a number of ways including participation in signaling pathways required for DNA synthesis, control of receptor turnover, actin cytoskeleton rearrangements and motility, and survival are discussed.
KW - Mitogenesis
KW - Phosphotyrosine
KW - Src
KW - Survival
KW - Ubiquitination
UR - http://www.scopus.com/inward/record.url?scp=7944237784&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=7944237784&partnerID=8YFLogxK
U2 - 10.1038/sj.onc.1208079
DO - 10.1038/sj.onc.1208079
M3 - Article
C2 - 15489913
AN - SCOPUS:7944237784
VL - 23
SP - 7957
EP - 7968
JO - Oncogene
JF - Oncogene
SN - 0950-9232
IS - 48 REV. ISS. 7
ER -