The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces

Daniel J. Gianoli, Sean Kohles, Nancy A. Burnham, Melissa B. Clark, Christopher A. Brown, James N. Kenealy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The feasibility of using the atomic force microscope (AFM) to locate individual cells on a roughened implant surface, and detach an adhered cell while measuring reaction forces was explored. Test samples from four different types of implant surfaces were prepared from commercially pure titanium (CPTi). These surface preparations included: machined, acid- etched (Osseotite), titanium plasma spray coated (TPS), and hydroxyapatite coated (HA). Preliminary data acquired for the roughness parameter (Ra) demonstrate that there is a clear difference between the four surface preparations.

Original languageEnglish (US)
Title of host publicationBioengineering, Proceedings of the Northeast Conference
EditorsJ.D. Enderle, L.L. Macfarlane
Pages5-6
Number of pages2
StatePublished - 2001
Externally publishedYes
Event27th IEEE Annual Northeast Bioengineering Conference - Storrs, CT, United States
Duration: Mar 31 2001Apr 1 2001

Other

Other27th IEEE Annual Northeast Bioengineering Conference
CountryUnited States
CityStorrs, CT
Period3/31/014/1/01

Fingerprint

Atomic force microscopy
Adhesion
Titanium
Durapatite
Hydroxyapatite
Microscopes
Surface roughness
Plasmas
Acids

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

Gianoli, D. J., Kohles, S., Burnham, N. A., Clark, M. B., Brown, C. A., & Kenealy, J. N. (2001). The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces. In J. D. Enderle, & L. L. Macfarlane (Eds.), Bioengineering, Proceedings of the Northeast Conference (pp. 5-6)

The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces. / Gianoli, Daniel J.; Kohles, Sean; Burnham, Nancy A.; Clark, Melissa B.; Brown, Christopher A.; Kenealy, James N.

Bioengineering, Proceedings of the Northeast Conference. ed. / J.D. Enderle; L.L. Macfarlane. 2001. p. 5-6.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gianoli, DJ, Kohles, S, Burnham, NA, Clark, MB, Brown, CA & Kenealy, JN 2001, The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces. in JD Enderle & LL Macfarlane (eds), Bioengineering, Proceedings of the Northeast Conference. pp. 5-6, 27th IEEE Annual Northeast Bioengineering Conference, Storrs, CT, United States, 3/31/01.
Gianoli DJ, Kohles S, Burnham NA, Clark MB, Brown CA, Kenealy JN. The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces. In Enderle JD, Macfarlane LL, editors, Bioengineering, Proceedings of the Northeast Conference. 2001. p. 5-6
Gianoli, Daniel J. ; Kohles, Sean ; Burnham, Nancy A. ; Clark, Melissa B. ; Brown, Christopher A. ; Kenealy, James N. / The feasibility of atomic force microscopy as a cytodetachment technique to quantify osteoblastic adhesion with implant surfaces. Bioengineering, Proceedings of the Northeast Conference. editor / J.D. Enderle ; L.L. Macfarlane. 2001. pp. 5-6
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