The efficacy of ketorolac as an adjunct to the bier block for controlling postoperative pain following nontraumatic hand and wrist surgery

Jesse J. Rivera, Dante J. Villecco, Bryan K. Dehner, Joseph F. Burkard, Lisa Osborne Smith, Joseph E. Pellegrini

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Research indicates that using a combination of ketorolac and lidocaine in the administration of a Bier block results in significant postoperative analgesia and decreased inflammation; however, the optimal dose of ketorolac to coadminister with the local anesthetic has not been established. This study was performed to determine if a 20-mg dose of ketorolac is effective in providing prolonged postoperative analgesia without adverse effects. A total of 55 patients (29 lidocaine-ketorolac, 26 lidocaine-placebo) were enrolled in this randomized, double-blind, placebo controlled study. Pain was measured using a 0 to 10 visual analogue scale and analysis of postoperative analgesic requirements. Incidence of bruising and postoperative analgesic satisfaction scores were determined 48 hours following discharge. No difference in demographic variables, adverse effect profiles, or satisfaction scores was noted between groups. Visual analogue scale scores were increased in the placebo group in the hospital but not following discharge to home. There was also a prolonged time to postoperative analgesic requests in the ketorolac group compared with the placebo group following discharge to home, achieving statistical significance for the time to second analgesic request (P = .012). Based on the results of this study we recommend that 20 mg ketorolac be considered in intravenous regional anesthesia.

Original languageEnglish (US)
Pages (from-to)341-345
Number of pages5
JournalAANA journal
Volume76
Issue number5
StatePublished - Oct 1 2008
Externally publishedYes

Fingerprint

Ketorolac
Postoperative Pain
Wrist
Hand
Analgesics
Lidocaine
Placebos
Visual Analog Scale
Analgesia
Intravenous Anesthesia
Conduction Anesthesia
Local Anesthetics
Demography
Inflammation
Pain
Incidence
Research

Keywords

  • Bier block
  • Hand surgery
  • Intravenous regional anesthesia
  • Ketorolac
  • Outpatient surgery

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Medical–Surgical
  • Advanced and Specialized Nursing

Cite this

The efficacy of ketorolac as an adjunct to the bier block for controlling postoperative pain following nontraumatic hand and wrist surgery. / Rivera, Jesse J.; Villecco, Dante J.; Dehner, Bryan K.; Burkard, Joseph F.; Osborne Smith, Lisa; Pellegrini, Joseph E.

In: AANA journal, Vol. 76, No. 5, 01.10.2008, p. 341-345.

Research output: Contribution to journalArticle

Rivera, Jesse J. ; Villecco, Dante J. ; Dehner, Bryan K. ; Burkard, Joseph F. ; Osborne Smith, Lisa ; Pellegrini, Joseph E. / The efficacy of ketorolac as an adjunct to the bier block for controlling postoperative pain following nontraumatic hand and wrist surgery. In: AANA journal. 2008 ; Vol. 76, No. 5. pp. 341-345.
@article{2e6d3d6ff5d14a30866c2b24edfc0ac3,
title = "The efficacy of ketorolac as an adjunct to the bier block for controlling postoperative pain following nontraumatic hand and wrist surgery",
abstract = "Research indicates that using a combination of ketorolac and lidocaine in the administration of a Bier block results in significant postoperative analgesia and decreased inflammation; however, the optimal dose of ketorolac to coadminister with the local anesthetic has not been established. This study was performed to determine if a 20-mg dose of ketorolac is effective in providing prolonged postoperative analgesia without adverse effects. A total of 55 patients (29 lidocaine-ketorolac, 26 lidocaine-placebo) were enrolled in this randomized, double-blind, placebo controlled study. Pain was measured using a 0 to 10 visual analogue scale and analysis of postoperative analgesic requirements. Incidence of bruising and postoperative analgesic satisfaction scores were determined 48 hours following discharge. No difference in demographic variables, adverse effect profiles, or satisfaction scores was noted between groups. Visual analogue scale scores were increased in the placebo group in the hospital but not following discharge to home. There was also a prolonged time to postoperative analgesic requests in the ketorolac group compared with the placebo group following discharge to home, achieving statistical significance for the time to second analgesic request (P = .012). Based on the results of this study we recommend that 20 mg ketorolac be considered in intravenous regional anesthesia.",
keywords = "Bier block, Hand surgery, Intravenous regional anesthesia, Ketorolac, Outpatient surgery",
author = "Rivera, {Jesse J.} and Villecco, {Dante J.} and Dehner, {Bryan K.} and Burkard, {Joseph F.} and {Osborne Smith}, Lisa and Pellegrini, {Joseph E.}",
year = "2008",
month = "10",
day = "1",
language = "English (US)",
volume = "76",
pages = "341--345",
journal = "AANA Journal",
issn = "0094-6354",
publisher = "AANA Publishing Inc.",
number = "5",

}

TY - JOUR

T1 - The efficacy of ketorolac as an adjunct to the bier block for controlling postoperative pain following nontraumatic hand and wrist surgery

AU - Rivera, Jesse J.

AU - Villecco, Dante J.

AU - Dehner, Bryan K.

AU - Burkard, Joseph F.

AU - Osborne Smith, Lisa

AU - Pellegrini, Joseph E.

PY - 2008/10/1

Y1 - 2008/10/1

N2 - Research indicates that using a combination of ketorolac and lidocaine in the administration of a Bier block results in significant postoperative analgesia and decreased inflammation; however, the optimal dose of ketorolac to coadminister with the local anesthetic has not been established. This study was performed to determine if a 20-mg dose of ketorolac is effective in providing prolonged postoperative analgesia without adverse effects. A total of 55 patients (29 lidocaine-ketorolac, 26 lidocaine-placebo) were enrolled in this randomized, double-blind, placebo controlled study. Pain was measured using a 0 to 10 visual analogue scale and analysis of postoperative analgesic requirements. Incidence of bruising and postoperative analgesic satisfaction scores were determined 48 hours following discharge. No difference in demographic variables, adverse effect profiles, or satisfaction scores was noted between groups. Visual analogue scale scores were increased in the placebo group in the hospital but not following discharge to home. There was also a prolonged time to postoperative analgesic requests in the ketorolac group compared with the placebo group following discharge to home, achieving statistical significance for the time to second analgesic request (P = .012). Based on the results of this study we recommend that 20 mg ketorolac be considered in intravenous regional anesthesia.

AB - Research indicates that using a combination of ketorolac and lidocaine in the administration of a Bier block results in significant postoperative analgesia and decreased inflammation; however, the optimal dose of ketorolac to coadminister with the local anesthetic has not been established. This study was performed to determine if a 20-mg dose of ketorolac is effective in providing prolonged postoperative analgesia without adverse effects. A total of 55 patients (29 lidocaine-ketorolac, 26 lidocaine-placebo) were enrolled in this randomized, double-blind, placebo controlled study. Pain was measured using a 0 to 10 visual analogue scale and analysis of postoperative analgesic requirements. Incidence of bruising and postoperative analgesic satisfaction scores were determined 48 hours following discharge. No difference in demographic variables, adverse effect profiles, or satisfaction scores was noted between groups. Visual analogue scale scores were increased in the placebo group in the hospital but not following discharge to home. There was also a prolonged time to postoperative analgesic requests in the ketorolac group compared with the placebo group following discharge to home, achieving statistical significance for the time to second analgesic request (P = .012). Based on the results of this study we recommend that 20 mg ketorolac be considered in intravenous regional anesthesia.

KW - Bier block

KW - Hand surgery

KW - Intravenous regional anesthesia

KW - Ketorolac

KW - Outpatient surgery

UR - http://www.scopus.com/inward/record.url?scp=53749096205&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=53749096205&partnerID=8YFLogxK

M3 - Article

VL - 76

SP - 341

EP - 345

JO - AANA Journal

JF - AANA Journal

SN - 0094-6354

IS - 5

ER -