The corneas of rats, rabbits, and monkeys were wounded and ophthalmic ointments immediately applied. The rate of re-epithelization of corneal abrasions or healing of keratectomies with or without the application of commercial ointments was measured. The various non-emulsive ointments bases included white petrolatum or mineral oil with or without lanolin. In addition, some ointments contained antibiotics, anti-inflammatory corticosteroid, boric acid, and preservatives. There was no evidence to indicate that current ophthalmic ointments alone or in combinations with the ophthalmic drugs tested interfered with corneal wound healing.
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