The effect of ophthalmic ointments on corneal wound healing

Calvin Hanna, Frederick T. Fraunfelder, Melanie Cable, Rufus E. Hardberger

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The corneas of rats, rabbits, and monkeys were wounded and ophthalmic ointments immediately applied. The rate of re-epithelization of corneal abrasions or healing of keratectomies with or without the application of commercial ointments was measured. The various non-emulsive ointments bases included white petrolatum or mineral oil with or without lanolin. In addition, some ointments contained antibiotics, anti-inflammatory corticosteroid, boric acid, and preservatives. There was no evidence to indicate that current ophthalmic ointments alone or in combinations with the ophthalmic drugs tested interfered with corneal wound healing.

Original languageEnglish (US)
Pages (from-to)193-200
Number of pages8
JournalAmerican journal of ophthalmology
Volume76
Issue number2
DOIs
StatePublished - Aug 1973

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ASJC Scopus subject areas

  • Ophthalmology

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