The effect of norgestrel and clogestone on the spontaneous motility of the human fallopian tube

M. G. Elder, Leslie Myatt, G. Chaudhuri

Research output: Contribution to journalArticle

Abstract

Spontaneous isometric contractions in vitro of both isthmic and ampullary parts of the human fallopian tube were studied. The tubes were obtained during the early luteal phase of the menstrual cycle from patients undergoing abdominal hysterectomy and who had ingested clogestone acetate or norgestrel, either 1 or 12 hours prior to the experiment. A dose of 150 μg dl-norgestrel given orally 12 hours preoperatively caused a significant increase in the frequency of spontaneous isometric contractions together with a significant reduction in the area under the curve for each contraction. The possible effect of this altered pattern of motility is discussed.

Original languageEnglish (US)
Pages (from-to)61-64
Number of pages4
JournalInternational Journal of Fertility
Volume23
Issue number1
StatePublished - 1978
Externally publishedYes

Fingerprint

Norgestrel
Isometric Contraction
Fallopian Tubes
Luteal Phase
Hysterectomy
Area Under Curve
clogestone

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

The effect of norgestrel and clogestone on the spontaneous motility of the human fallopian tube. / Elder, M. G.; Myatt, Leslie; Chaudhuri, G.

In: International Journal of Fertility, Vol. 23, No. 1, 1978, p. 61-64.

Research output: Contribution to journalArticle

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