The effect of methylmercury chloride and triethyllead chloride on sulphate incorporation into sulphatides of rat cerebellum slices during myelination

I. Grundt, H. Offner, G. Konat, J. Clausen

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Abstract

Cerebellum slices from rat brain were incubated in a medium containing (35S) sulphate. The incorporation of (35S) into sulphatide was measured. The tissue slices were dhown to incorporate (:5S) even after 44hr of incubation. The maximal incorporation was observed when cerebellum from 12 to 15 day old rats was used. An equimolar inhibitory effect on the (35S) uptake into sulphatide was induced by 25 μM methylmercury chloride and by 2.5 μM triethyllead chloride.

Original languageEnglish (US)
Pages (from-to)166-171
Number of pages6
JournalENVIRONM.PHYSIOL.BIOCHEM.
Volume4
Issue number4
StatePublished - Dec 1 1974

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ASJC Scopus subject areas

  • Medicine(all)

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