The effect of maternal body mass index on perinatal outcomes in women with diabetes

Nicole Marshall, Camelia Guild, Yvonne W. Cheng, Aaron Caughey, Donna R. Halloran

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective To determine the effect of increasing maternal obesity, including superobesity (body mass index [BMI] ≥ 50 kg/m2), on perinatal outcomes in women with diabetes. Study Design Retrospective cohort study of birth records for all live-born nonanomalous singleton infants ≥ 37 weeks' gestation born to Missouri residents with diabetes from 2000 to 2006. Women with either pregestational or gestational diabetes were included. Results There were 14,595 births to women with diabetes meeting study criteria, including 7,082 women with a BMI > 30 kg/m2 (48.5%). Compared with normal-weight women with diabetes, increasing BMI category, especially superobesity, was associated with a significantly increased risk for preeclampsia (adjusted relative risk [aRR] 3.6, 95% confidence interval [CI] 2.5, 5.2) and macrosomia (aRR 3.0, 95% CI 1.8, 5.40). The majority of nulliparous obese women with diabetes delivered via cesarean including 50.5% of obese, 61.4% of morbidly obese, and 69.8% of superobese women. The incidence of primary elective cesarean among nulliparous women with diabetes increased significantly with increasing maternal BMI with over 33% of morbidly obese and 39% of superobese women with diabetes delivering electively by cesarean. Conclusion Increasing maternal obesity in women with diabetes is significantly associated with higher risks of perinatal complications, especially cesarean delivery.

Original languageEnglish (US)
Pages (from-to)249-256
Number of pages8
JournalAmerican Journal of Perinatology
Volume31
Issue number3
DOIs
StatePublished - Mar 2014

Fingerprint

Body Mass Index
Mothers
Obesity
Confidence Intervals
Birth Certificates
Gestational Diabetes
Pre-Eclampsia
Cohort Studies
Retrospective Studies
Parturition
Weights and Measures
Pregnancy
Incidence

Keywords

  • cesarean
  • diabetes
  • obesity
  • superobesity

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

The effect of maternal body mass index on perinatal outcomes in women with diabetes. / Marshall, Nicole; Guild, Camelia; Cheng, Yvonne W.; Caughey, Aaron; Halloran, Donna R.

In: American Journal of Perinatology, Vol. 31, No. 3, 03.2014, p. 249-256.

Research output: Contribution to journalArticle

Marshall, Nicole ; Guild, Camelia ; Cheng, Yvonne W. ; Caughey, Aaron ; Halloran, Donna R. / The effect of maternal body mass index on perinatal outcomes in women with diabetes. In: American Journal of Perinatology. 2014 ; Vol. 31, No. 3. pp. 249-256.
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