The effect of hypotension and hypotensive technique on cerebral ischaemia and the dimension of the ischaemic penumbra

J. C. Drummond, D. J. Cole, H. M. Shapiro, Mark Zornow

Research output: Contribution to journalArticle

Abstract

Temporary cerebral vascular occlusion may occur either electively or in urgent circumstances during intracranial vascular procedures. On occasion, induced hypotension is employed simultaneously. It is accepted that the combination should result in a larger area of ischaemia. However, the phenomenon has not been examined systematically nor has the influence of the specific hypotensive techniques been evaluated. The present study examined the extent of ischaemia and the dimension of the ischaemic penumbra following middle cerebral artery occlusion (MCAO) during normotension and during three hypotensive regimens.

Original languageEnglish (US)
JournalCanadian Journal of Anaesthesia
Volume35
Issue number3 II
StatePublished - 1988
Externally publishedYes

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Brain Ischemia
Hypotension
Blood Vessels
Ischemia
Controlled Hypotension
Middle Cerebral Artery Infarction

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

The effect of hypotension and hypotensive technique on cerebral ischaemia and the dimension of the ischaemic penumbra. / Drummond, J. C.; Cole, D. J.; Shapiro, H. M.; Zornow, Mark.

In: Canadian Journal of Anaesthesia, Vol. 35, No. 3 II, 1988.

Research output: Contribution to journalArticle

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