TY - JOUR
T1 - The acoustic lens design and in vivo use of a multifunctional catheter combining intracardiac ultrasound imaging and electrophysiology sensing
AU - Stephens, Douglas N.
AU - Cannata, Jonathan
AU - Liu, Ruibin
AU - Zhao, Jian Zhong
AU - Shung, K. Kirk
AU - Nguyen, Hien
AU - Chia, Raymond
AU - Dentinger, Aaron
AU - Wildes, Douglas
AU - Thomenius, Kai E.
AU - Mahajan, Aman
AU - Shivkumar, Kalyanam
AU - Kim, Kang
AU - O'Donnell, Matthew
AU - Sahn, David
N1 - Funding Information:
Manuscript received June 10, 2007; accepted September 20, 2007. This research was performed with funding from NIH/NHLBI grant R01 HL067647. D. N. Stephens is with the Department of Biomedical Engineering, University of California, Davis, CA (e-mail: dnstephens@ ucdavis.edu). J. Cannata, R. Liu, J.-Z. Zhao, and K. K. Shung are with the Resource Center for Medical Ultrasonic Transducer Technology, University of Southern California, Los Angeles, CA. H. Nguyen and R. Chia are with Irvine Biomedical Corporation, Inc., Irvine, CA. A. Dentinger, D. Wildes, and K. E. Thomenius are with General Electric Global Research, Niskayuna, NY. A. Mahajan and K. Shivkumar are with the David Geffen School of Medicine, University of California, Los Angeles, CA. K. Kim is with the Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI. M. O’Donnell is with the College of Engineering, University of Washington, Seattle, WA. D. Sahn is with the Oregon Health and Sciences University, Portland, OR. Digital Object Identifier 10.1109/TUFFC.2008.685
PY - 2008
Y1 - 2008
N2 - A multifunctional 9F intracardiac imaging and electrophysiology mapping catheter was developed and tested to help guide diagnostic and therapeutic intracardiac electrophysiology (EP) procedures. The catheter tip includes a 7.25-MHz, 64-element, side-looking phased array for high resolution sector scanning. Multiple electrophysiology mapping sensors were mounted as ring electrodes near the array for electrocardiographic synchronization of ultrasound images. The catheter array elevation beam performance in particular was investigated. An acoustic lens for the distal tip array designed with a round cross section can produce an acceptable elevation beam shape; however, the velocity of sound in the lens material should be approximately 155 m/s slower than in tissue for the best beam shape and wide bandwidth performance. To help establish the catheter's unique ability for integration with electrophysiology interventional procedures, it was used in vivo in a porcine animal model, and demonstrated both useful intracardiac echocardiographic visualization and simultaneous 3- D positional information using integrated electroanatomical mapping techniques. The catheter also performed well in high frame rate imaging, color flow imaging, and strain rate imaging of atrial and ventricular structures.
AB - A multifunctional 9F intracardiac imaging and electrophysiology mapping catheter was developed and tested to help guide diagnostic and therapeutic intracardiac electrophysiology (EP) procedures. The catheter tip includes a 7.25-MHz, 64-element, side-looking phased array for high resolution sector scanning. Multiple electrophysiology mapping sensors were mounted as ring electrodes near the array for electrocardiographic synchronization of ultrasound images. The catheter array elevation beam performance in particular was investigated. An acoustic lens for the distal tip array designed with a round cross section can produce an acceptable elevation beam shape; however, the velocity of sound in the lens material should be approximately 155 m/s slower than in tissue for the best beam shape and wide bandwidth performance. To help establish the catheter's unique ability for integration with electrophysiology interventional procedures, it was used in vivo in a porcine animal model, and demonstrated both useful intracardiac echocardiographic visualization and simultaneous 3- D positional information using integrated electroanatomical mapping techniques. The catheter also performed well in high frame rate imaging, color flow imaging, and strain rate imaging of atrial and ventricular structures.
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U2 - 10.1109/TUFFC.2008.685
DO - 10.1109/TUFFC.2008.685
M3 - Article
C2 - 18407850
AN - SCOPUS:44849111324
SN - 0885-3010
VL - 55
SP - 602
EP - 618
JO - IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
JF - IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
IS - 3
M1 - 4476368
ER -