Surviving ovarian cancer: An affair between defective DNA repair and RB1

Guang Peng; Gordon B. Mills

doi:10.1158/1078-0432.CCR-17-3022

Surviving ovarian cancer: An affair between defective DNA repair and RB1

Guang Peng, Gordon B. Mills

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Detailed clinical and molecular evaluation of large cohorts of exceptional survivors provides an unprecedented opportunity to identify mechanisms underlying long-term survival that can drive future therapeutic approaches and biomarker development. Exceptional survivors of high-grade serous ovarian cancer demonstrate concurrent disruption of homologous recombination DNA repair and retinoblastoma protein.

Original language	English (US)
Pages (from-to)	508-510
Number of pages	3
Journal	Clinical Cancer Research
Volume	24
Issue number	3
DOIs	https://doi.org/10.1158/1078-0432.CCR-17-3022
State	Published - Feb 1 2018
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1158/1078-0432.CCR-17-3022

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title = "Surviving ovarian cancer: An affair between defective DNA repair and RB1",

abstract = "Detailed clinical and molecular evaluation of large cohorts of exceptional survivors provides an unprecedented opportunity to identify mechanisms underlying long-term survival that can drive future therapeutic approaches and biomarker development. Exceptional survivors of high-grade serous ovarian cancer demonstrate concurrent disruption of homologous recombination DNA repair and retinoblastoma protein.",

author = "Guang Peng and Mills, {Gordon B.}",

note = "Publisher Copyright: {\textcopyright} 2017 American Association for Cancer Research.",

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AU - Mills, Gordon B.

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AB - Detailed clinical and molecular evaluation of large cohorts of exceptional survivors provides an unprecedented opportunity to identify mechanisms underlying long-term survival that can drive future therapeutic approaches and biomarker development. Exceptional survivors of high-grade serous ovarian cancer demonstrate concurrent disruption of homologous recombination DNA repair and retinoblastoma protein.

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Surviving ovarian cancer: An affair between defective DNA repair and RB1

Abstract

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