Surviving ovarian cancer

An affair between defective DNA repair and RB1

Guang Peng, Gordon Mills

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Detailed clinical and molecular evaluation of large cohorts of exceptional survivors provides an unprecedented opportunity to identify mechanisms underlying long-term survival that can drive future therapeutic approaches and biomarker development. Exceptional survivors of high-grade serous ovarian cancer demonstrate concurrent disruption of homologous recombination DNA repair and retinoblastoma protein.

Original languageEnglish (US)
Pages (from-to)508-510
Number of pages3
JournalClinical Cancer Research
Volume24
Issue number3
DOIs
StatePublished - Feb 1 2018
Externally publishedYes

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Recombinational DNA Repair
Retinoblastoma Protein
DNA Repair
Ovarian Neoplasms
Biomarkers
Therapeutics

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Surviving ovarian cancer : An affair between defective DNA repair and RB1. / Peng, Guang; Mills, Gordon.

In: Clinical Cancer Research, Vol. 24, No. 3, 01.02.2018, p. 508-510.

Research output: Contribution to journalArticle

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