Surgeon and hospital characteristics as predictors of major adverse outcomes following colon cancer surgery: Understanding the volume-outcome relationship

Kevin Billingsley, Arden M. Morris, Jason A. Dominitz, Barbara Matthews, Sharon Dobie, William Barlow, George E. Wright, Laura Mae Baldwin

    Research output: Contribution to journalArticle

    106 Citations (Scopus)

    Abstract

    Hypothesis: Although numerous studies have demonstrated an association between surgical volume and improved outcome in cancer surgery, the specific structures and mechanisms of care that are associated with volume and lead to improved outcomes remain poorly defined. We hypothesize that there are modifiable surgeon and hospital characteristics that explain observed volume-outcome relationships. Design: Retrospective cohort study. Setting: Surveillance, Epidemiology, and End Results cancer registry areas. Patients: Patients aged 66 years and older, diagnosed and surgically treated for stage I, II, or III colon cancer between 1992 and 1996 (n=22 672). Main Outcome Measures: Thirty-day postoperative mortality and 30-day postoperative procedural interventions, including reoperation and image-guided percutaneous procedures. Results: Surgeon volume, but not hospital volume, is a significant predictor of postoperative procedural intervention (adjusted odds ratio for very high-volume surgeons vs low-volume surgeons, 0.79; 95% confidence interval, 0.64-0.98). In the unadjusted analyses, high hospital volume (odds ratio, 0.67; 95% confidence interval, 0.56-0.81) and very high hospital volume (odds ratio, 0.65; 95% confidence interval, 0.54-0.79) is associated with lower postoperative mortality. Postoperative procedural intervention is not a significant mediator of the relationship between hospital volume and mortality. A single variable - the presence of sophisticated clinical services - was the most important explanatory variable underlying the relationship between hospital volume and mortality. Conclusions: Very high surgeon volume is associated with a reduction in surgical complications. However, the association between increasing hospital volume and postoperative mortality appears to derive mainly from a full spectrum of clinical services that may facilitate the prompt recognition and treatment of complications.

    Original languageEnglish (US)
    JournalArchives of Surgery
    Volume142
    Issue number1
    DOIs
    StatePublished - 2007

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    Colonic Neoplasms
    High-Volume Hospitals
    Odds Ratio
    Confidence Intervals
    Hospital Mortality
    Mortality
    Reoperation
    Registries
    Neoplasms
    Epidemiology
    Cohort Studies
    Retrospective Studies
    Outcome Assessment (Health Care)
    Surgeons
    Therapeutics

    ASJC Scopus subject areas

    • Surgery

    Cite this

    Surgeon and hospital characteristics as predictors of major adverse outcomes following colon cancer surgery : Understanding the volume-outcome relationship. / Billingsley, Kevin; Morris, Arden M.; Dominitz, Jason A.; Matthews, Barbara; Dobie, Sharon; Barlow, William; Wright, George E.; Baldwin, Laura Mae.

    In: Archives of Surgery, Vol. 142, No. 1, 2007.

    Research output: Contribution to journalArticle

    Billingsley, Kevin ; Morris, Arden M. ; Dominitz, Jason A. ; Matthews, Barbara ; Dobie, Sharon ; Barlow, William ; Wright, George E. ; Baldwin, Laura Mae. / Surgeon and hospital characteristics as predictors of major adverse outcomes following colon cancer surgery : Understanding the volume-outcome relationship. In: Archives of Surgery. 2007 ; Vol. 142, No. 1.
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    abstract = "Hypothesis: Although numerous studies have demonstrated an association between surgical volume and improved outcome in cancer surgery, the specific structures and mechanisms of care that are associated with volume and lead to improved outcomes remain poorly defined. We hypothesize that there are modifiable surgeon and hospital characteristics that explain observed volume-outcome relationships. Design: Retrospective cohort study. Setting: Surveillance, Epidemiology, and End Results cancer registry areas. Patients: Patients aged 66 years and older, diagnosed and surgically treated for stage I, II, or III colon cancer between 1992 and 1996 (n=22 672). Main Outcome Measures: Thirty-day postoperative mortality and 30-day postoperative procedural interventions, including reoperation and image-guided percutaneous procedures. Results: Surgeon volume, but not hospital volume, is a significant predictor of postoperative procedural intervention (adjusted odds ratio for very high-volume surgeons vs low-volume surgeons, 0.79; 95{\%} confidence interval, 0.64-0.98). In the unadjusted analyses, high hospital volume (odds ratio, 0.67; 95{\%} confidence interval, 0.56-0.81) and very high hospital volume (odds ratio, 0.65; 95{\%} confidence interval, 0.54-0.79) is associated with lower postoperative mortality. Postoperative procedural intervention is not a significant mediator of the relationship between hospital volume and mortality. A single variable - the presence of sophisticated clinical services - was the most important explanatory variable underlying the relationship between hospital volume and mortality. Conclusions: Very high surgeon volume is associated with a reduction in surgical complications. However, the association between increasing hospital volume and postoperative mortality appears to derive mainly from a full spectrum of clinical services that may facilitate the prompt recognition and treatment of complications.",
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    AU - Dobie, Sharon

    AU - Barlow, William

    AU - Wright, George E.

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