Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription

Medicine & Life Sciences

• naphthol AS-E 100%
• Cyclic AMP Response Element-Binding Protein 53%
• Structure-Activity Relationship 49%
• Antineoplastic Agents 40%
• Genes 16%
• Protein Kinases 6%
• Phosphotransferases 5%
• G-Protein-Coupled Receptor Kinases 5%
• tyrosine receptor 5%
• CREB-Binding Protein 5%
• Neoplasms 4%
• A549 Cells 3%
• MCF-7 Cells 3%
• Protein Binding 3%
• Carrier Proteins 2%
• Electrons 2%
• Transcription Factors 2%
• Poisons 2%
• In Vitro Techniques 1%
• Pharmaceutical Preparations 1%
• Therapeutics 0%

Chemical Compounds

• Naphthol 52%
• Antineoplastic Agent 37%
• Structure-Activity Relationship 36%
• Protein 17%
• Drug Target 4%
• Tyrosine 3%
• Toxic 2%
• Molecule 1%