Steroid and gonadotropin secretion in a patient with a 30-year history of virilization due to lipoid-cell ovarian tumor

Ariel L. Barkan; Fernando Cassorla; D. Lynn Loriaux; Robert P. Kelch; John C. Marshall

doi:10.1097/00006254-198503000-00015

Steroid and gonadotropin secretion in a patient with a 30-year history of virilization due to lipoid-cell ovarian tumor

Ariel L. Barkan, Fernando Cassorla, D. Lynn Loriaux, Robert P. Kelch, John C. Marshall

Research output: Contribution to journal › Article › peer-review

Abstract

This report describes a patient with long-standing virilization caused by the androgen-producing lipoid-cell tumor of the ovary. Detailed studies of androgen secretion, both under basal conditions and after various suppressive and stimulatory tests, were performed. The steroid biosynthetic pattern of the tumor was studied by simultaneous measurements of steroids in the ovarian veins and in peripheral blood, and was subsequently correlated with direct measurements of enzyme activities in excised tumor tissue. Additionally, a detailed investigation of both basal and gonadotropin-releasing hormone-stimulated gonadotropin secretion was performed before and after removal of the tumor.

Original language	English (US)
Pages (from-to)	168-170
Number of pages	3
Journal	Obstetrical and Gynecological Survey
Volume	40
Issue number	3
DOIs	https://doi.org/10.1097/00006254-198503000-00015
State	Published - Mar 1985
Externally published	Yes

ASJC Scopus subject areas

Obstetrics and Gynecology

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title = "Steroid and gonadotropin secretion in a patient with a 30-year history of virilization due to lipoid-cell ovarian tumor",

abstract = "This report describes a patient with long-standing virilization caused by the androgen-producing lipoid-cell tumor of the ovary. Detailed studies of androgen secretion, both under basal conditions and after various suppressive and stimulatory tests, were performed. The steroid biosynthetic pattern of the tumor was studied by simultaneous measurements of steroids in the ovarian veins and in peripheral blood, and was subsequently correlated with direct measurements of enzyme activities in excised tumor tissue. Additionally, a detailed investigation of both basal and gonadotropin-releasing hormone-stimulated gonadotropin secretion was performed before and after removal of the tumor.",

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AU - Barkan, Ariel L.

AU - Cassorla, Fernando

AU - Loriaux, D. Lynn

AU - Kelch, Robert P.

AU - Marshall, John C.

PY - 1985/3

Y1 - 1985/3

N2 - This report describes a patient with long-standing virilization caused by the androgen-producing lipoid-cell tumor of the ovary. Detailed studies of androgen secretion, both under basal conditions and after various suppressive and stimulatory tests, were performed. The steroid biosynthetic pattern of the tumor was studied by simultaneous measurements of steroids in the ovarian veins and in peripheral blood, and was subsequently correlated with direct measurements of enzyme activities in excised tumor tissue. Additionally, a detailed investigation of both basal and gonadotropin-releasing hormone-stimulated gonadotropin secretion was performed before and after removal of the tumor.

AB - This report describes a patient with long-standing virilization caused by the androgen-producing lipoid-cell tumor of the ovary. Detailed studies of androgen secretion, both under basal conditions and after various suppressive and stimulatory tests, were performed. The steroid biosynthetic pattern of the tumor was studied by simultaneous measurements of steroids in the ovarian veins and in peripheral blood, and was subsequently correlated with direct measurements of enzyme activities in excised tumor tissue. Additionally, a detailed investigation of both basal and gonadotropin-releasing hormone-stimulated gonadotropin secretion was performed before and after removal of the tumor.

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Steroid and gonadotropin secretion in a patient with a 30-year history of virilization due to lipoid-cell ovarian tumor

Abstract

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