Stereotactic ventral intermedial thalamotomy for the treatment of essential tremor: Results of a series of 37 patients

M. Cenk Akbostanci, Konstantin V. Slavin, Kim Burchiel

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

We have analyzed 43 ventral intermediate thalamotomies performed in our center for treatment of medically intractable essential tremor (ET) in 37 patients. The mean age of patients was 70.9 years (range 42-84), duration of symptoms 33.3 years (1-65). The surgery in all cases was performed with stereotactic technique using MRI or CT localization. Intraoperative neuro-physiological confirmation of the target location was obtained using a macrostimulation technique. All patients experienced either complete abolition of the contralateral tremor or significant improvement in tremor intensity immediately after the surgery. At follow-up examination 1-13 months after the operation, 60.5% of patients had no tremor, and 13.9% had mild residual tremor without interference with daily life. Tremor recurrence was observed in 5 patients, all of whom underwent repeat ventral intermedial (VIM) thalamotomy with excellent results. Transient problems with speech and motor functions were observed after 15 thalamotomies, permanent hemiparesis and speech difficulties were seen in 6 patients. We conclude that VIM thalamotomy is a highly effective procedure for medically intractable ET and may be performed with no mortality and low morbidity rate. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)174-177
Number of pages4
JournalStereotactic and Functional Neurosurgery
Volume72
Issue number2-4
StatePublished - Apr 2000

Fingerprint

Essential Tremor
Tremor
Therapeutics
Stereotaxic Techniques
Paresis
Morbidity
Recurrence
Mortality

Keywords

  • Essential tremor
  • Stereotaxis
  • Thalamotomy

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Stereotactic ventral intermedial thalamotomy for the treatment of essential tremor : Results of a series of 37 patients. / Akbostanci, M. Cenk; Slavin, Konstantin V.; Burchiel, Kim.

In: Stereotactic and Functional Neurosurgery, Vol. 72, No. 2-4, 04.2000, p. 174-177.

Research output: Contribution to journalArticle

@article{b308cb78bdbe4d0dae1e77305e10b469,
title = "Stereotactic ventral intermedial thalamotomy for the treatment of essential tremor: Results of a series of 37 patients",
abstract = "We have analyzed 43 ventral intermediate thalamotomies performed in our center for treatment of medically intractable essential tremor (ET) in 37 patients. The mean age of patients was 70.9 years (range 42-84), duration of symptoms 33.3 years (1-65). The surgery in all cases was performed with stereotactic technique using MRI or CT localization. Intraoperative neuro-physiological confirmation of the target location was obtained using a macrostimulation technique. All patients experienced either complete abolition of the contralateral tremor or significant improvement in tremor intensity immediately after the surgery. At follow-up examination 1-13 months after the operation, 60.5{\%} of patients had no tremor, and 13.9{\%} had mild residual tremor without interference with daily life. Tremor recurrence was observed in 5 patients, all of whom underwent repeat ventral intermedial (VIM) thalamotomy with excellent results. Transient problems with speech and motor functions were observed after 15 thalamotomies, permanent hemiparesis and speech difficulties were seen in 6 patients. We conclude that VIM thalamotomy is a highly effective procedure for medically intractable ET and may be performed with no mortality and low morbidity rate. Copyright (C) 2000 S. Karger AG, Basel.",
keywords = "Essential tremor, Stereotaxis, Thalamotomy",
author = "Akbostanci, {M. Cenk} and Slavin, {Konstantin V.} and Kim Burchiel",
year = "2000",
month = "4",
language = "English (US)",
volume = "72",
pages = "174--177",
journal = "Stereotactic and Functional Neurosurgery",
issn = "1011-6125",
publisher = "S. Karger AG",
number = "2-4",

}

TY - JOUR

T1 - Stereotactic ventral intermedial thalamotomy for the treatment of essential tremor

T2 - Results of a series of 37 patients

AU - Akbostanci, M. Cenk

AU - Slavin, Konstantin V.

AU - Burchiel, Kim

PY - 2000/4

Y1 - 2000/4

N2 - We have analyzed 43 ventral intermediate thalamotomies performed in our center for treatment of medically intractable essential tremor (ET) in 37 patients. The mean age of patients was 70.9 years (range 42-84), duration of symptoms 33.3 years (1-65). The surgery in all cases was performed with stereotactic technique using MRI or CT localization. Intraoperative neuro-physiological confirmation of the target location was obtained using a macrostimulation technique. All patients experienced either complete abolition of the contralateral tremor or significant improvement in tremor intensity immediately after the surgery. At follow-up examination 1-13 months after the operation, 60.5% of patients had no tremor, and 13.9% had mild residual tremor without interference with daily life. Tremor recurrence was observed in 5 patients, all of whom underwent repeat ventral intermedial (VIM) thalamotomy with excellent results. Transient problems with speech and motor functions were observed after 15 thalamotomies, permanent hemiparesis and speech difficulties were seen in 6 patients. We conclude that VIM thalamotomy is a highly effective procedure for medically intractable ET and may be performed with no mortality and low morbidity rate. Copyright (C) 2000 S. Karger AG, Basel.

AB - We have analyzed 43 ventral intermediate thalamotomies performed in our center for treatment of medically intractable essential tremor (ET) in 37 patients. The mean age of patients was 70.9 years (range 42-84), duration of symptoms 33.3 years (1-65). The surgery in all cases was performed with stereotactic technique using MRI or CT localization. Intraoperative neuro-physiological confirmation of the target location was obtained using a macrostimulation technique. All patients experienced either complete abolition of the contralateral tremor or significant improvement in tremor intensity immediately after the surgery. At follow-up examination 1-13 months after the operation, 60.5% of patients had no tremor, and 13.9% had mild residual tremor without interference with daily life. Tremor recurrence was observed in 5 patients, all of whom underwent repeat ventral intermedial (VIM) thalamotomy with excellent results. Transient problems with speech and motor functions were observed after 15 thalamotomies, permanent hemiparesis and speech difficulties were seen in 6 patients. We conclude that VIM thalamotomy is a highly effective procedure for medically intractable ET and may be performed with no mortality and low morbidity rate. Copyright (C) 2000 S. Karger AG, Basel.

KW - Essential tremor

KW - Stereotaxis

KW - Thalamotomy

UR - http://www.scopus.com/inward/record.url?scp=0342700211&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0342700211&partnerID=8YFLogxK

M3 - Article

C2 - 10853074

AN - SCOPUS:0342700211

VL - 72

SP - 174

EP - 177

JO - Stereotactic and Functional Neurosurgery

JF - Stereotactic and Functional Neurosurgery

SN - 1011-6125

IS - 2-4

ER -