TY - JOUR
T1 - State of the clinical science of perioperative brain health
T2 - report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018
AU - Mahanna-Gabrielli, Elizabeth
AU - Schenning, Katie J.
AU - Eriksson, Lars I.
AU - Browndyke, Jeffrey N.
AU - Wright, Clinton B.
AU - Evered, Lis
AU - Scott, David A.
AU - Wang, Nae Yah
AU - Brown, Charles H.
AU - Oh, Esther
AU - Purdon, Patrick
AU - Inouye, Sharon
AU - Berger, Miles
AU - Whittington, Robert A.
AU - Deiner, Stacie
N1 - Publisher Copyright:
© 2019 British Journal of Anaesthesia
PY - 2019/10
Y1 - 2019/10
N2 - Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families, and caregivers. Reports of patients who were ‘never the same’ prompted a scientific inquiry into the nature of what patients have experienced. In June 2018, the ASA Brain Health Initiative held a summit to discuss the state of the science on perioperative cognition, and to create an implementation plan for patients and providers leveraging the current evidence. This group included representatives from the AARP (formerly the American Association of Retired Persons), American College of Surgeons, American Heart Association, and Alzheimer's Association Perioperative Cognition and Delirium Professional Interest Area. This paper summarises the state of the relevant clinical science, including risk factors, identification and diagnosis, prognosis, disparities, outcomes, and treatment of perioperative neurocognitive disorders. Finally, we discuss gaps in current knowledge with suggestions for future directions and opportunities for clinical and translational projects.
AB - Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families, and caregivers. Reports of patients who were ‘never the same’ prompted a scientific inquiry into the nature of what patients have experienced. In June 2018, the ASA Brain Health Initiative held a summit to discuss the state of the science on perioperative cognition, and to create an implementation plan for patients and providers leveraging the current evidence. This group included representatives from the AARP (formerly the American Association of Retired Persons), American College of Surgeons, American Heart Association, and Alzheimer's Association Perioperative Cognition and Delirium Professional Interest Area. This paper summarises the state of the relevant clinical science, including risk factors, identification and diagnosis, prognosis, disparities, outcomes, and treatment of perioperative neurocognitive disorders. Finally, we discuss gaps in current knowledge with suggestions for future directions and opportunities for clinical and translational projects.
KW - anaesthesia
KW - delirium
KW - geriatrics
KW - neurocognitive disorders
KW - perioperative brain health
KW - postoperative cognitive dysfunction
KW - postoperative complications
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U2 - 10.1016/j.bja.2019.07.004
DO - 10.1016/j.bja.2019.07.004
M3 - Article
C2 - 31439308
AN - SCOPUS:85070702175
SN - 0007-0912
VL - 123
SP - 464
EP - 478
JO - British journal of anaesthesia
JF - British journal of anaesthesia
IS - 4
ER -