TY - JOUR
T1 - Smoking, obesity, and survival in squamous cell carcinoma of the vulva
AU - Kirschner, Carolyn V.
AU - Yordan, Edgardo L.
AU - De Geest, Koen
AU - Wilbanks, George D.
PY - 1995/1
Y1 - 1995/1
N2 - One hundred thirty-six patients with invasive squamous cell carcinoma of the vulva were studied retrospectively to determine prognostic factors for survival. In the regression analysis, three variables were statistically significantly related to survival: smoking history, tumor size, and node status. Smokers had a 6.3 times greater risk of death than nonsmokers, node positivity imparted an 8.3 times greater risk than node negativity, and for each 1-cm increase in the size of the tumor, the risk of death increased by 46%. A relative decrease in survival in smokers was observed, despite a younger age and fewer positive nodes at diagnosis compared to nonsmokers. Increased surveillance in these patients may be warranted.
AB - One hundred thirty-six patients with invasive squamous cell carcinoma of the vulva were studied retrospectively to determine prognostic factors for survival. In the regression analysis, three variables were statistically significantly related to survival: smoking history, tumor size, and node status. Smokers had a 6.3 times greater risk of death than nonsmokers, node positivity imparted an 8.3 times greater risk than node negativity, and for each 1-cm increase in the size of the tumor, the risk of death increased by 46%. A relative decrease in survival in smokers was observed, despite a younger age and fewer positive nodes at diagnosis compared to nonsmokers. Increased surveillance in these patients may be warranted.
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U2 - 10.1006/gyno.1995.1013
DO - 10.1006/gyno.1995.1013
M3 - Article
C2 - 7821852
AN - SCOPUS:0028924964
SN - 0090-8258
VL - 56
SP - 79
EP - 84
JO - Gynecologic oncology
JF - Gynecologic oncology
IS - 1
ER -