Single needle revision of failing filtration blebs: A retrospective comparative case series with 5-fluorouracil and mitomycin C

Neal Palejwala, Parul Ichhpujani, Ghasem Fakhraie, Jonathan S. Myers, Marlene R. Moster, L. Jay Katz

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

PURPOSE. To assess the success of needling in failed filtration blebs and the potential benefit of using either 5-fluorouracil (5-FU) or mitomycin C (MMC). METHODS. In this retrospective, comparative observational case series, 107 eyes that underwent needle revision with either 5-FU or MMC between July 2003 and May 2008 at Wills Eye Institute were selected. Exclusion criteria included follow-up less than 1 month and a history of glaucoma drainage device. Intraocular pressure (IOP) and number of glaucoma medications were recorded preoperatively and postoperatively. Success was defined as >20% decrease in IOP if glaucoma medications were resumed or

Original languageEnglish (US)
Pages (from-to)1026-1034
Number of pages9
JournalEuropean Journal of Ophthalmology
Volume20
Issue number6
StatePublished - Nov 2010
Externally publishedYes

Fingerprint

Mitomycin
Blister
Fluorouracil
Glaucoma
Needles
Intraocular Pressure
Drainage
Equipment and Supplies

Keywords

  • 5-Fluorouracil
  • Failed bleb
  • Mitomycin C
  • Needling

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Palejwala, N., Ichhpujani, P., Fakhraie, G., Myers, J. S., Moster, M. R., & Katz, L. J. (2010). Single needle revision of failing filtration blebs: A retrospective comparative case series with 5-fluorouracil and mitomycin C. European Journal of Ophthalmology, 20(6), 1026-1034.

Single needle revision of failing filtration blebs : A retrospective comparative case series with 5-fluorouracil and mitomycin C. / Palejwala, Neal; Ichhpujani, Parul; Fakhraie, Ghasem; Myers, Jonathan S.; Moster, Marlene R.; Katz, L. Jay.

In: European Journal of Ophthalmology, Vol. 20, No. 6, 11.2010, p. 1026-1034.

Research output: Contribution to journalArticle

Palejwala, N, Ichhpujani, P, Fakhraie, G, Myers, JS, Moster, MR & Katz, LJ 2010, 'Single needle revision of failing filtration blebs: A retrospective comparative case series with 5-fluorouracil and mitomycin C', European Journal of Ophthalmology, vol. 20, no. 6, pp. 1026-1034.
Palejwala, Neal ; Ichhpujani, Parul ; Fakhraie, Ghasem ; Myers, Jonathan S. ; Moster, Marlene R. ; Katz, L. Jay. / Single needle revision of failing filtration blebs : A retrospective comparative case series with 5-fluorouracil and mitomycin C. In: European Journal of Ophthalmology. 2010 ; Vol. 20, No. 6. pp. 1026-1034.
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