Simultaneous monitoring of voltammetric and ion-selective electrodes in mammalian brain

G. Nagy, B. Moghaddam, A. Oke, R. N. Adams

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A new technique of simultaneously recording from ion-selective and voltammetric microelectrodes in vivo allows one to measure concomitant ionic and monoamine neurotransmitter fluxes in the extracellular fluid space of the brain. Examples are presented of the results obtained with various drug and stimulus applications. The time correlations of the ionic and neurotransmitter fluxes are especially useful in attempting to better understand the possible interactions of these chemical dynamics with neuronal functioning.

Original languageEnglish (US)
Pages (from-to)119-124
Number of pages6
JournalNeuroscience Letters
Issue number2
StatePublished - Apr 9 1985
Externally publishedYes


  • central nervous system ion fluxes
  • ion-selective electrode
  • neurotransmitter release
  • voltammetric electrode

ASJC Scopus subject areas

  • Neuroscience(all)


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