Short-term paroxetine treatment does not alter the motor response to levodopa in PD

Kathryn A. Chung, Nichole E. Carlson, John G. Nutt

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

The authors examined the motor effects of 2 weeks of paroxetine, a serotonin reuptake inhibitor (SSRI), and placebo on responses to 2-hour levodopa infusions in 14 subjects with Parkinson disease. Paroxetine did not affect tapping scores or dyskinesia. Baseline walking speed (preinfusion) increased on paroxetine, often associated with an increased subjective perception of worsened balance.

Original languageEnglish (US)
Pages (from-to)1797-1798
Number of pages2
JournalNeurology
Volume64
Issue number10
DOIs
StatePublished - May 24 2005

ASJC Scopus subject areas

  • Clinical Neurology

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