Short-term paroxetine treatment does not alter the motor response to levodopa in PD

Kathryn A. Chung; Nichole E. Carlson; John G. Nutt

doi:10.1212/01.WNL.0000161841.41885.80

Short-term paroxetine treatment does not alter the motor response to levodopa in PD

Kathryn A. Chung, Nichole E. Carlson, John G. Nutt

Neurology

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

The authors examined the motor effects of 2 weeks of paroxetine, a serotonin reuptake inhibitor (SSRI), and placebo on responses to 2-hour levodopa infusions in 14 subjects with Parkinson disease. Paroxetine did not affect tapping scores or dyskinesia. Baseline walking speed (preinfusion) increased on paroxetine, often associated with an increased subjective perception of worsened balance.

Original language	English (US)
Pages (from-to)	1797-1798
Number of pages	2
Journal	Neurology
Volume	64
Issue number	10
DOIs	https://doi.org/10.1212/01.WNL.0000161841.41885.80
State	Published - May 24 2005

ASJC Scopus subject areas

Clinical Neurology

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10.1212/01.WNL.0000161841.41885.80

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AB - The authors examined the motor effects of 2 weeks of paroxetine, a serotonin reuptake inhibitor (SSRI), and placebo on responses to 2-hour levodopa infusions in 14 subjects with Parkinson disease. Paroxetine did not affect tapping scores or dyskinesia. Baseline walking speed (preinfusion) increased on paroxetine, often associated with an increased subjective perception of worsened balance.

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Short-term paroxetine treatment does not alter the motor response to levodopa in PD

Abstract

ASJC Scopus subject areas

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