Self-assembling amphiphilic siderophores from marine bacteria

J. S. Martinez, G. P. Zhang, P. D. Holt, H. T. Jung, C. J. Carrano, Margo Haygood, Alison Butler

Research output: Contribution to journalArticle

237 Citations (Scopus)

Abstract

Most aerobic bacteria secrete siderophores to facilitate iron acquisition. Two families of siderophores were isolated from strains belonging to two different genera of marine bacteria. The aquachelins, from Halomonas aquamarina strain DS40M3, and the marinobactins, from Marinobacter sp. strains DS40M6 and DS40M8, each contain a unique peptidic head group that coordinates iron(III) and an appendage of one of a series of fatty acid moieties. These siderophores have low critical micelle concentrations (CMCs). In the absence of iron, the marinobactins are present as micelles at concentrations exceeding their CMC; upon addition of iron(III), the micelles undergo a spontaneous phase change to form vesicles. These observations suggest that unique iron acquisition mechanisms may have evolved in marine bacteria.

Original languageEnglish (US)
Pages (from-to)1245-1247
Number of pages3
JournalScience
Volume287
Issue number5456
DOIs
StatePublished - Feb 18 2000
Externally publishedYes

Fingerprint

Siderophores
Micelles
Iron
Bacteria
Marinobacter
Halomonas
Aerobic Bacteria
Fatty Acids

ASJC Scopus subject areas

  • General

Cite this

Martinez, J. S., Zhang, G. P., Holt, P. D., Jung, H. T., Carrano, C. J., Haygood, M., & Butler, A. (2000). Self-assembling amphiphilic siderophores from marine bacteria. Science, 287(5456), 1245-1247. https://doi.org/10.1126/science.287.5456.1245

Self-assembling amphiphilic siderophores from marine bacteria. / Martinez, J. S.; Zhang, G. P.; Holt, P. D.; Jung, H. T.; Carrano, C. J.; Haygood, Margo; Butler, Alison.

In: Science, Vol. 287, No. 5456, 18.02.2000, p. 1245-1247.

Research output: Contribution to journalArticle

Martinez, JS, Zhang, GP, Holt, PD, Jung, HT, Carrano, CJ, Haygood, M & Butler, A 2000, 'Self-assembling amphiphilic siderophores from marine bacteria', Science, vol. 287, no. 5456, pp. 1245-1247. https://doi.org/10.1126/science.287.5456.1245
Martinez JS, Zhang GP, Holt PD, Jung HT, Carrano CJ, Haygood M et al. Self-assembling amphiphilic siderophores from marine bacteria. Science. 2000 Feb 18;287(5456):1245-1247. https://doi.org/10.1126/science.287.5456.1245
Martinez, J. S. ; Zhang, G. P. ; Holt, P. D. ; Jung, H. T. ; Carrano, C. J. ; Haygood, Margo ; Butler, Alison. / Self-assembling amphiphilic siderophores from marine bacteria. In: Science. 2000 ; Vol. 287, No. 5456. pp. 1245-1247.
@article{6313f5f9a3184bce901e0b7976e08b99,
title = "Self-assembling amphiphilic siderophores from marine bacteria",
abstract = "Most aerobic bacteria secrete siderophores to facilitate iron acquisition. Two families of siderophores were isolated from strains belonging to two different genera of marine bacteria. The aquachelins, from Halomonas aquamarina strain DS40M3, and the marinobactins, from Marinobacter sp. strains DS40M6 and DS40M8, each contain a unique peptidic head group that coordinates iron(III) and an appendage of one of a series of fatty acid moieties. These siderophores have low critical micelle concentrations (CMCs). In the absence of iron, the marinobactins are present as micelles at concentrations exceeding their CMC; upon addition of iron(III), the micelles undergo a spontaneous phase change to form vesicles. These observations suggest that unique iron acquisition mechanisms may have evolved in marine bacteria.",
author = "Martinez, {J. S.} and Zhang, {G. P.} and Holt, {P. D.} and Jung, {H. T.} and Carrano, {C. J.} and Margo Haygood and Alison Butler",
year = "2000",
month = "2",
day = "18",
doi = "10.1126/science.287.5456.1245",
language = "English (US)",
volume = "287",
pages = "1245--1247",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "5456",

}

TY - JOUR

T1 - Self-assembling amphiphilic siderophores from marine bacteria

AU - Martinez, J. S.

AU - Zhang, G. P.

AU - Holt, P. D.

AU - Jung, H. T.

AU - Carrano, C. J.

AU - Haygood, Margo

AU - Butler, Alison

PY - 2000/2/18

Y1 - 2000/2/18

N2 - Most aerobic bacteria secrete siderophores to facilitate iron acquisition. Two families of siderophores were isolated from strains belonging to two different genera of marine bacteria. The aquachelins, from Halomonas aquamarina strain DS40M3, and the marinobactins, from Marinobacter sp. strains DS40M6 and DS40M8, each contain a unique peptidic head group that coordinates iron(III) and an appendage of one of a series of fatty acid moieties. These siderophores have low critical micelle concentrations (CMCs). In the absence of iron, the marinobactins are present as micelles at concentrations exceeding their CMC; upon addition of iron(III), the micelles undergo a spontaneous phase change to form vesicles. These observations suggest that unique iron acquisition mechanisms may have evolved in marine bacteria.

AB - Most aerobic bacteria secrete siderophores to facilitate iron acquisition. Two families of siderophores were isolated from strains belonging to two different genera of marine bacteria. The aquachelins, from Halomonas aquamarina strain DS40M3, and the marinobactins, from Marinobacter sp. strains DS40M6 and DS40M8, each contain a unique peptidic head group that coordinates iron(III) and an appendage of one of a series of fatty acid moieties. These siderophores have low critical micelle concentrations (CMCs). In the absence of iron, the marinobactins are present as micelles at concentrations exceeding their CMC; upon addition of iron(III), the micelles undergo a spontaneous phase change to form vesicles. These observations suggest that unique iron acquisition mechanisms may have evolved in marine bacteria.

UR - http://www.scopus.com/inward/record.url?scp=0034681576&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034681576&partnerID=8YFLogxK

U2 - 10.1126/science.287.5456.1245

DO - 10.1126/science.287.5456.1245

M3 - Article

VL - 287

SP - 1245

EP - 1247

JO - Science

JF - Science

SN - 0036-8075

IS - 5456

ER -