We have treated 13 adult patients with many types of PWS. The light source was a flashlamp-pumped tunable dye laser (Candela Model LFDL-1) operating at 577 nm and at a pulse duration of 360 μsec. The treatment involved: a) determination of energy per area (E0) required to produce a purpuric well-defined macule on normal skin; b) a therapeutic test, (3 pairs of 3 mm diameter spots at E0 of 1.5, 2, and 2.5x the purpura threshold energy per area); c) the choice of the optimal E0 (6-10 J/cm2) of step 'b' based on evaluation of test spots at 6 weeks; and d) evaluation and repeated treatments bi-monthly as necessary. No anesthesia was needed. Patients received one to five treatments at 6-8 week intervals on the same diseased area with a follow-up of 3 to 13 months. Biopsies were taken from three patients before irradiation, immediately after, at 24 hours, at one week, and at one month. The results were excellent in 5 cases, good in 6, and fair in 2. There was improvement in all treated lesions for all patients. No patients developed hypo- or hypertrophic scarring, but one patient developed hypopigmented macules after the first treatment.
|Translated title of the contribution||Selective photothermolysis: Application in laser therapy of port wine stains|
|Number of pages||10|
|Journal||Annales de Dermatologie et de Venereologie|
|State||Published - Jan 1 1987|
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