Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Goksemin Acar, Feridun Acar, Jonathan Miller, David Spencer, Kim Burchiel

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The aim of this study was to retrospectively determine if patients with medically refractory epilepsy, due to hippocampal sclerosis, who underwent selective amygdalohippocampectomy (SAH) with a transcortical approach experienced improved seizure outcome. Thirty-nine patients with mesial temporal lobe epilepsy and hippocampal sclerosis were included in the study. The mean follow-up was 25.88 ± 17.69 months. Antiepileptic medication use and seizure frequency were significantly reduced after SAH. After surgery, 32 patients (82.05%) were completely seizure free (Engel class IA), and 2 patients experienced transient memory difficulty. In conclusion, SAH with a transcortical approach can lead to favorable seizure control with a low irreversible complication risk.

Original languageEnglish (US)
Pages (from-to)314-319
Number of pages6
JournalStereotactic and Functional Neurosurgery
Volume86
Issue number5
DOIs
StatePublished - Oct 2008

Fingerprint

Temporal Lobe Epilepsy
Seizures
Sclerosis
Anticonvulsants
Epilepsy

Keywords

  • Hippocampal sclerosis
  • Mesial temporal lobe epilepsy
  • Seizure outcome
  • Selective amygdalohippocampectomy, transcortical

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy. / Acar, Goksemin; Acar, Feridun; Miller, Jonathan; Spencer, David; Burchiel, Kim.

In: Stereotactic and Functional Neurosurgery, Vol. 86, No. 5, 10.2008, p. 314-319.

Research output: Contribution to journalArticle

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