Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Goksemin Acar, Feridun Acar, Jonathan Miller, David C. Spencer, Kim J. Burchiel

Research output: Contribution to journalArticle

21 Scopus citations


The aim of this study was to retrospectively determine if patients with medically refractory epilepsy, due to hippocampal sclerosis, who underwent selective amygdalohippocampectomy (SAH) with a transcortical approach experienced improved seizure outcome. Thirty-nine patients with mesial temporal lobe epilepsy and hippocampal sclerosis were included in the study. The mean follow-up was 25.88 ± 17.69 months. Antiepileptic medication use and seizure frequency were significantly reduced after SAH. After surgery, 32 patients (82.05%) were completely seizure free (Engel class IA), and 2 patients experienced transient memory difficulty. In conclusion, SAH with a transcortical approach can lead to favorable seizure control with a low irreversible complication risk.

Original languageEnglish (US)
Pages (from-to)314-319
Number of pages6
JournalStereotactic and Functional Neurosurgery
Issue number5
StatePublished - Oct 1 2008



  • Hippocampal sclerosis
  • Mesial temporal lobe epilepsy
  • Seizure outcome
  • Selective amygdalohippocampectomy, transcortical

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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