Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Goksemin Acar, Feridun Acar, Jonathan Miller, David C. Spencer, Kim J. Burchiel

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The aim of this study was to retrospectively determine if patients with medically refractory epilepsy, due to hippocampal sclerosis, who underwent selective amygdalohippocampectomy (SAH) with a transcortical approach experienced improved seizure outcome. Thirty-nine patients with mesial temporal lobe epilepsy and hippocampal sclerosis were included in the study. The mean follow-up was 25.88 ± 17.69 months. Antiepileptic medication use and seizure frequency were significantly reduced after SAH. After surgery, 32 patients (82.05%) were completely seizure free (Engel class IA), and 2 patients experienced transient memory difficulty. In conclusion, SAH with a transcortical approach can lead to favorable seizure control with a low irreversible complication risk.

Original languageEnglish (US)
Pages (from-to)314-319
Number of pages6
JournalStereotactic and Functional Neurosurgery
Volume86
Issue number5
DOIs
StatePublished - Oct 1 2008

Keywords

  • Hippocampal sclerosis
  • Mesial temporal lobe epilepsy
  • Seizure outcome
  • Selective amygdalohippocampectomy, transcortical

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy'. Together they form a unique fingerprint.

Cite this