Salpingoscopy

Light microscopic and electron microscopic correlations

Avner Hershlag, David Seifer, Maria L. Carcangiu, Dorothy L. Patton, Michael P. Diamond, Alan H. DeCherney

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

In order to examine the ability of salpingoscopy to diagnose intratubal pathology, 32 fallopian tubes were evaluated salpingoscopically and histologically. Both flexible and rigid salpingoscopes were used, and observations were documented by intratubal photography. Salpingoscopic criteria were established and each criterion assigned a numerical value. Each tube was evaluated for patency, mucosal fold architecture, erythema, adhesions, and dilatation. Based on these criteria, tubes were graded as normal or as abnormal with mild, moderate, or severe changes. Histologically, each tube was evaluated for patency, epithelial changes, vascularity, dilatation, adhesions, and active inflammation. Six tubes with significant histologic findings and two histologically normal fallopian tubes were also examined by transmission electron microscopy. In five discordant cases, histology revealed epithelial and stromal changes not detected by salpingoscopy. Fallopian tubes with severe disease were diagnosed by both methods. Transmission electron microscopy of histologically abnormal tubes showed flattening of the epithelium with markedly reduced ciliary distribution, degenerating secretory epithelial cells with large intracellular vacuoles, and swollen nuclei containing sparse chromatin. Our results indicate that salpingoscopic observations are consistent with histologic findings when endotubal disease is severe. However, moderate pathologic changes as documented by light microscopy and transmission electron microscopy were frequently not diagnosed salpingoscopically, even with magnification.

Original languageEnglish (US)
Pages (from-to)399-405
Number of pages7
JournalObstetrics and Gynecology
Volume77
Issue number3
StatePublished - 1991
Externally publishedYes

Fingerprint

Fallopian Tubes
Transmission Electron Microscopy
Electrons
Light
Dilatation
Photography
Erythema
Vacuoles
Chromatin
Microscopy
Histology
Epithelium
Epithelial Cells
Pathology
Inflammation

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Hershlag, A., Seifer, D., Carcangiu, M. L., Patton, D. L., Diamond, M. P., & DeCherney, A. H. (1991). Salpingoscopy: Light microscopic and electron microscopic correlations. Obstetrics and Gynecology, 77(3), 399-405.

Salpingoscopy : Light microscopic and electron microscopic correlations. / Hershlag, Avner; Seifer, David; Carcangiu, Maria L.; Patton, Dorothy L.; Diamond, Michael P.; DeCherney, Alan H.

In: Obstetrics and Gynecology, Vol. 77, No. 3, 1991, p. 399-405.

Research output: Contribution to journalArticle

Hershlag, A, Seifer, D, Carcangiu, ML, Patton, DL, Diamond, MP & DeCherney, AH 1991, 'Salpingoscopy: Light microscopic and electron microscopic correlations', Obstetrics and Gynecology, vol. 77, no. 3, pp. 399-405.
Hershlag A, Seifer D, Carcangiu ML, Patton DL, Diamond MP, DeCherney AH. Salpingoscopy: Light microscopic and electron microscopic correlations. Obstetrics and Gynecology. 1991;77(3):399-405.
Hershlag, Avner ; Seifer, David ; Carcangiu, Maria L. ; Patton, Dorothy L. ; Diamond, Michael P. ; DeCherney, Alan H. / Salpingoscopy : Light microscopic and electron microscopic correlations. In: Obstetrics and Gynecology. 1991 ; Vol. 77, No. 3. pp. 399-405.
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