Abstract
Optical properties of biological tissue can change as a result of thermal denaturation due to temperature rise; a familiar example is whitening observed in cooking egg-white. Changes in optical properties with temperature have been reported in the literature. Temperature rise due to laser irradiation is a function of the optical properties of tissue which themselves are a function of temperature of the tissue. This creates a coupling between light and temperature fields for biological tissue under laser irradiation. The effects of this coupling on the temperature response and light distribution may play an important role in dosimetry consideration for therapeutic as well as diagnostic application of lasers in medicine. In a previous study this problem was addressed in one dimension, for short irradiation exposures, using certain simplifying assumptions. The purpose of this research was to develop a mathematical model for dynamic optical changes with thermal denaturation and a computer program for simulation of these effects for a multi-dimensional geometry.
| Original language | English (US) |
|---|---|
| Title of host publication | Laser-Tissue Interaction III |
| Publisher | SPIE |
| Pages | 228-235 |
| Number of pages | 8 |
| Volume | 1646 |
| ISBN (Electronic) | 9780819407924 |
| DOIs | |
| State | Published - Aug 7 1992 |
| Externally published | Yes |
| Event | Laser-Tissue Interaction III 1992 - Los Angeles, United States Duration: Jan 19 1992 → Jan 24 1992 |
Other
| Other | Laser-Tissue Interaction III 1992 |
|---|---|
| Country | United States |
| City | Los Angeles |
| Period | 1/19/92 → 1/24/92 |
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ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering
Cite this
Role of temperature dependence of optical properties in laser irradiation of biological tissue. / Rastegar, S.; Kim, B. M.; Jacques, Steven.
Laser-Tissue Interaction III. Vol. 1646 SPIE, 1992. p. 228-235.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Role of temperature dependence of optical properties in laser irradiation of biological tissue
AU - Rastegar, S.
AU - Kim, B. M.
AU - Jacques, Steven
PY - 1992/8/7
Y1 - 1992/8/7
N2 - Optical properties of biological tissue can change as a result of thermal denaturation due to temperature rise; a familiar example is whitening observed in cooking egg-white. Changes in optical properties with temperature have been reported in the literature. Temperature rise due to laser irradiation is a function of the optical properties of tissue which themselves are a function of temperature of the tissue. This creates a coupling between light and temperature fields for biological tissue under laser irradiation. The effects of this coupling on the temperature response and light distribution may play an important role in dosimetry consideration for therapeutic as well as diagnostic application of lasers in medicine. In a previous study this problem was addressed in one dimension, for short irradiation exposures, using certain simplifying assumptions. The purpose of this research was to develop a mathematical model for dynamic optical changes with thermal denaturation and a computer program for simulation of these effects for a multi-dimensional geometry.
AB - Optical properties of biological tissue can change as a result of thermal denaturation due to temperature rise; a familiar example is whitening observed in cooking egg-white. Changes in optical properties with temperature have been reported in the literature. Temperature rise due to laser irradiation is a function of the optical properties of tissue which themselves are a function of temperature of the tissue. This creates a coupling between light and temperature fields for biological tissue under laser irradiation. The effects of this coupling on the temperature response and light distribution may play an important role in dosimetry consideration for therapeutic as well as diagnostic application of lasers in medicine. In a previous study this problem was addressed in one dimension, for short irradiation exposures, using certain simplifying assumptions. The purpose of this research was to develop a mathematical model for dynamic optical changes with thermal denaturation and a computer program for simulation of these effects for a multi-dimensional geometry.
UR - http://www.scopus.com/inward/record.url?scp=85010174451&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85010174451&partnerID=8YFLogxK
U2 - 10.1117/12.137464
DO - 10.1117/12.137464
M3 - Conference contribution
AN - SCOPUS:85010174451
VL - 1646
SP - 228
EP - 235
BT - Laser-Tissue Interaction III
PB - SPIE
ER -