Risk factors for kala-azar in Bangladesh

Caryn Bern, Allen W. Hightower, Rajib Chowdhury, Mustakim Ali, Josef Amann, Yukiko Wagatsuma, Rashidul Haque, Katie Kurkjian, Louise Vaz, Moarrita Begum, Tangin Akter, Catherine B. Cetre-Sossah, Indu B. Ahluwalia, Ellen Dotson, W. Evan Secor, Robert F. Breiman, James H. Maguire

Research output: Contribution to journalArticle

126 Citations (Scopus)

Abstract

Since 1990, South Asia has experienced a resurgence of kala-azar (visceral leishmaniasis). To determine risk factors for kala-azar, we performed cross-sectional surveys over a 3-year period in a Bangladeshi community. By history, active case detection, and serologic screening, 155 of 2,356 residents had kala-azar with onset from 2000 to 2003. Risk was highest for persons 3-45 years of age, and no significant difference by sex was seen. In age-adjusted multivariable models, 3 factors were identified: proximity to a previous kala-azar patient (odds ratio [OR] 25.4, 95% confidence interval [CI] 15-44 within household; OR 3.2 95% CI 1.7-6.1 within 50 m), bed net use in summer (OR 0.7, 95% CI 0.53-0.93), and cattle per 1,000 m 2 (OR 0.8, 95% CI 0.70-0.94]). No difference was seen by income, education, or occupation; land ownership or other assets; housing materials and condition; or keeping goats or chickens inside bedrooms. Our data confirm strong clustering and suggest that insecticide-treated nets could be effective in preventing kala-azar.

Original languageEnglish (US)
Pages (from-to)655-662
Number of pages8
JournalEmerging Infectious Diseases
Volume11
Issue number5
StatePublished - May 2005
Externally publishedYes

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Visceral Leishmaniasis
Bangladesh
Odds Ratio
Confidence Intervals
Ownership
Insecticides
Occupations
Goats
Sex Characteristics
Cluster Analysis
Chickens
Cross-Sectional Studies
History
Education

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Bern, C., Hightower, A. W., Chowdhury, R., Ali, M., Amann, J., Wagatsuma, Y., ... Maguire, J. H. (2005). Risk factors for kala-azar in Bangladesh. Emerging Infectious Diseases, 11(5), 655-662.

Risk factors for kala-azar in Bangladesh. / Bern, Caryn; Hightower, Allen W.; Chowdhury, Rajib; Ali, Mustakim; Amann, Josef; Wagatsuma, Yukiko; Haque, Rashidul; Kurkjian, Katie; Vaz, Louise; Begum, Moarrita; Akter, Tangin; Cetre-Sossah, Catherine B.; Ahluwalia, Indu B.; Dotson, Ellen; Secor, W. Evan; Breiman, Robert F.; Maguire, James H.

In: Emerging Infectious Diseases, Vol. 11, No. 5, 05.2005, p. 655-662.

Research output: Contribution to journalArticle

Bern, C, Hightower, AW, Chowdhury, R, Ali, M, Amann, J, Wagatsuma, Y, Haque, R, Kurkjian, K, Vaz, L, Begum, M, Akter, T, Cetre-Sossah, CB, Ahluwalia, IB, Dotson, E, Secor, WE, Breiman, RF & Maguire, JH 2005, 'Risk factors for kala-azar in Bangladesh', Emerging Infectious Diseases, vol. 11, no. 5, pp. 655-662.
Bern C, Hightower AW, Chowdhury R, Ali M, Amann J, Wagatsuma Y et al. Risk factors for kala-azar in Bangladesh. Emerging Infectious Diseases. 2005 May;11(5):655-662.
Bern, Caryn ; Hightower, Allen W. ; Chowdhury, Rajib ; Ali, Mustakim ; Amann, Josef ; Wagatsuma, Yukiko ; Haque, Rashidul ; Kurkjian, Katie ; Vaz, Louise ; Begum, Moarrita ; Akter, Tangin ; Cetre-Sossah, Catherine B. ; Ahluwalia, Indu B. ; Dotson, Ellen ; Secor, W. Evan ; Breiman, Robert F. ; Maguire, James H. / Risk factors for kala-azar in Bangladesh. In: Emerging Infectious Diseases. 2005 ; Vol. 11, No. 5. pp. 655-662.
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