Risk factors and impact of non-Aspergillus mold infections following allogeneic HCT: A CIBMTR infection and immune reconstitution analysis

M. L. Riches, S. Trifilio, M. Chen, K. W. Ahn, A. Langston, H. M. Lazarus, D. I. Marks, R. Martino, Richard Maziarz, G. A. Papanicolou, J. R. Wingard, J. A H Young, C. L. Bennett

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Risk factors for non-Aspergillus mold infection (NAMI) and the impact on transplant outcome are poorly assessed in the current era of antifungal agents. Outcomes of 124 patients receiving allogeneic hematopoietic cell transplantation (HCT) diagnosed with either mucormycosis (n=72) or fusariosis (n=52) between days 0 and 365 after HCT are described and compared with a control cohort (n=11 856). Patients with NAMI had more advanced disease (mucormycois: 25%, fusariosis: 23% and controls: 18%; P=0.004) and were more likely to have a Karnofsky performance status (KPS)

Original languageEnglish (US)
Pages (from-to)277-282
Number of pages6
JournalBone Marrow Transplantation
Volume51
Issue number2
DOIs
StatePublished - Feb 1 2016

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ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Riches, M. L., Trifilio, S., Chen, M., Ahn, K. W., Langston, A., Lazarus, H. M., Marks, D. I., Martino, R., Maziarz, R., Papanicolou, G. A., Wingard, J. R., Young, J. A. H., & Bennett, C. L. (2016). Risk factors and impact of non-Aspergillus mold infections following allogeneic HCT: A CIBMTR infection and immune reconstitution analysis. Bone Marrow Transplantation, 51(2), 277-282. https://doi.org/10.1038/bmt.2015.263