Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma (Nature Neuroscience, (2020), 10.1038/s41593-020-0628-4)

Alexandra Garancher, Hiromichi Suzuki, Svasti Haricharan, Lianne Q. Chau, Meher Beigi Masihi, Jessica M. Rusert, Paula S. Norris, Florent Carrette, Megan M. Romero, Sorana A. Morrissy, Patryk Skowron, Florence M.G. Cavalli, Hamza Farooq, Vijay Ramaswamy, Steven J.M. Jones, Richard A. Moore, Andrew J. Mungall, Yussanne Ma, Nina Thiessen, Yisu LiAlaide Morcavallo, Lin Qi, Mari Kogiso, Yuchen Du, Patricia Baxter, Jacob J. Henderson, John R. Crawford, Michael L. Levy, James M. Olson, Yoon Jae Cho, Aniruddha J. Deshpande, Xiao Nan Li, Louis Chesler, Marco A. Marra, Harald Wajant, Oren J. Becher, Linda M. Bradley, Carl F. Ware, Michael D. Taylor, Robert J. Wechsler-Reya

Research output: Contribution to journalComment/debatepeer-review

Abstract

The authors are retracting this paper owing to issues with the integrity of the data presented. Specifically, inconsistencies in the flow cytometry data in Figs. 2d, 4b, 5c,d, 5g,h, 6a,b and 7a-d, and Extended Data Figs. 2b, 3a-i, and 6c-j were found, with selected experimental samples collected using different settings from their corresponding controls. Thus, the data in these figures do not reflect the true fluorescence of the samples in question. In addition, we have been unable to replicate the key in vivo findings in the paper, including those presented in Fig. 7e-h and Extended Data Fig. 8d-k. These concerns undermine our confidence in the study and we therefore wish to retract the article in its entirety. We deeply regret this incident and apologize to the scientific community.

Original languageEnglish (US)
Pages (from-to)127
Number of pages1
JournalNature Neuroscience
Volume25
Issue number1
DOIs
StatePublished - Jan 2022

ASJC Scopus subject areas

  • Neuroscience(all)

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