Retention of Host Embryonic Descemet Membrane in Endothelial Keratoplasty

Edwin S. Chen, Neda Shamie, Mark A. Terry, Paul M. Phillips, David Wilson

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

OBJECTIVE: To describe a case of retained host embryonic Descemet membrane (DM) after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Review of clinical findings in a case of DSAEK with retention of host embryonic DM. RESULTS: A geographic and patchy haze in the interface involving the visual axis was noted postoperatively as soon as 1 week after DSAEK surgery. This was noted on clinical exam and thought to be retained embryonic DM. Review of pathology on the explanted DM confirmed delamination of DM with absence of the anterior embryonic layer and only patchy areas of full-thickness DM. The haze was followed over time and did not regress over the first 6 months after surgery. It did not seem to affect vision significantly, and the patient achieved best spectacle-corrected vision of 20/30 by 6 months. CONCLUSIONS: Endothelial keratoplasty is a relatively new technique for posterior corneal transplantation. Variations in operative technique continue to be described. Delamination of DM during stripping can occur; however, retention of host embryonic DM in DSAEK surgery seems to be compatible with good vision.

Original languageEnglish (US)
Pages (from-to)351-353
Number of pages3
JournalCornea
Volume28
Issue number3
DOIs
StatePublished - Apr 2009

Fingerprint

Descemet Membrane
Corneal Transplantation
Descemet Stripping Endothelial Keratoplasty
Pathology

Keywords

  • Deep lamellar endothelial keratoplasty
  • Descemet stripping automated endothelial keratoplasty
  • Descemet stripping endothelial keratoplasty
  • DLEK
  • DSAEK
  • DSEK
  • EK
  • Endothelial keratoplasty
  • Lamellar keratoplasty
  • LK
  • Penetrating keratoplasty
  • PK

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Retention of Host Embryonic Descemet Membrane in Endothelial Keratoplasty. / Chen, Edwin S.; Shamie, Neda; Terry, Mark A.; Phillips, Paul M.; Wilson, David.

In: Cornea, Vol. 28, No. 3, 04.2009, p. 351-353.

Research output: Contribution to journalArticle

Chen, Edwin S. ; Shamie, Neda ; Terry, Mark A. ; Phillips, Paul M. ; Wilson, David. / Retention of Host Embryonic Descemet Membrane in Endothelial Keratoplasty. In: Cornea. 2009 ; Vol. 28, No. 3. pp. 351-353.
@article{bf7fbd82505c43499c2afa18fb1e0b53,
title = "Retention of Host Embryonic Descemet Membrane in Endothelial Keratoplasty",
abstract = "OBJECTIVE: To describe a case of retained host embryonic Descemet membrane (DM) after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Review of clinical findings in a case of DSAEK with retention of host embryonic DM. RESULTS: A geographic and patchy haze in the interface involving the visual axis was noted postoperatively as soon as 1 week after DSAEK surgery. This was noted on clinical exam and thought to be retained embryonic DM. Review of pathology on the explanted DM confirmed delamination of DM with absence of the anterior embryonic layer and only patchy areas of full-thickness DM. The haze was followed over time and did not regress over the first 6 months after surgery. It did not seem to affect vision significantly, and the patient achieved best spectacle-corrected vision of 20/30 by 6 months. CONCLUSIONS: Endothelial keratoplasty is a relatively new technique for posterior corneal transplantation. Variations in operative technique continue to be described. Delamination of DM during stripping can occur; however, retention of host embryonic DM in DSAEK surgery seems to be compatible with good vision.",
keywords = "Deep lamellar endothelial keratoplasty, Descemet stripping automated endothelial keratoplasty, Descemet stripping endothelial keratoplasty, DLEK, DSAEK, DSEK, EK, Endothelial keratoplasty, Lamellar keratoplasty, LK, Penetrating keratoplasty, PK",
author = "Chen, {Edwin S.} and Neda Shamie and Terry, {Mark A.} and Phillips, {Paul M.} and David Wilson",
year = "2009",
month = "4",
doi = "10.1097/ICO.0b013e3181861c6b",
language = "English (US)",
volume = "28",
pages = "351--353",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Retention of Host Embryonic Descemet Membrane in Endothelial Keratoplasty

AU - Chen, Edwin S.

AU - Shamie, Neda

AU - Terry, Mark A.

AU - Phillips, Paul M.

AU - Wilson, David

PY - 2009/4

Y1 - 2009/4

N2 - OBJECTIVE: To describe a case of retained host embryonic Descemet membrane (DM) after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Review of clinical findings in a case of DSAEK with retention of host embryonic DM. RESULTS: A geographic and patchy haze in the interface involving the visual axis was noted postoperatively as soon as 1 week after DSAEK surgery. This was noted on clinical exam and thought to be retained embryonic DM. Review of pathology on the explanted DM confirmed delamination of DM with absence of the anterior embryonic layer and only patchy areas of full-thickness DM. The haze was followed over time and did not regress over the first 6 months after surgery. It did not seem to affect vision significantly, and the patient achieved best spectacle-corrected vision of 20/30 by 6 months. CONCLUSIONS: Endothelial keratoplasty is a relatively new technique for posterior corneal transplantation. Variations in operative technique continue to be described. Delamination of DM during stripping can occur; however, retention of host embryonic DM in DSAEK surgery seems to be compatible with good vision.

AB - OBJECTIVE: To describe a case of retained host embryonic Descemet membrane (DM) after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Review of clinical findings in a case of DSAEK with retention of host embryonic DM. RESULTS: A geographic and patchy haze in the interface involving the visual axis was noted postoperatively as soon as 1 week after DSAEK surgery. This was noted on clinical exam and thought to be retained embryonic DM. Review of pathology on the explanted DM confirmed delamination of DM with absence of the anterior embryonic layer and only patchy areas of full-thickness DM. The haze was followed over time and did not regress over the first 6 months after surgery. It did not seem to affect vision significantly, and the patient achieved best spectacle-corrected vision of 20/30 by 6 months. CONCLUSIONS: Endothelial keratoplasty is a relatively new technique for posterior corneal transplantation. Variations in operative technique continue to be described. Delamination of DM during stripping can occur; however, retention of host embryonic DM in DSAEK surgery seems to be compatible with good vision.

KW - Deep lamellar endothelial keratoplasty

KW - Descemet stripping automated endothelial keratoplasty

KW - Descemet stripping endothelial keratoplasty

KW - DLEK

KW - DSAEK

KW - DSEK

KW - EK

KW - Endothelial keratoplasty

KW - Lamellar keratoplasty

KW - LK

KW - Penetrating keratoplasty

KW - PK

UR - http://www.scopus.com/inward/record.url?scp=67149124066&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67149124066&partnerID=8YFLogxK

U2 - 10.1097/ICO.0b013e3181861c6b

DO - 10.1097/ICO.0b013e3181861c6b

M3 - Article

C2 - 19387242

AN - SCOPUS:67149124066

VL - 28

SP - 351

EP - 353

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 3

ER -