Repolarization lability measured on 10-second ECG by spatial TT′ angle

Reproducibility and agreement with QT variability

Albert Feeny, Lichy Han, Larisa Tereshchenko

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    Background Reproducibility of spatial TT′ angle on the 10-second ECG and its agreement with QT variability has not been previously studied. Methods We analyzed 2 randomly selected 10-second segments within 3-minute resting orthogonal ECG in 172 healthy IDEAL study participants (age 38.1 ± 15.2 years, 50% male, 94% white). Repolarization lability was measured by the QT variance (QTV), short-term QT variability (STV(QT)), and spatial TT′ angle. Bland-Altman analysis was used to assess the agreement between different log-transformed metrics of repolarization lability, and to assess the reproducibility. Results The heart rate showed a very high reproducibility (bias 0.14%, Lin's rho-c = 0.99). As expected, noise suppression by averaging improves reproducibility. Agreement between two 10-second LogQTV was poor (bias - 0.04; 95% limits of agreement [- 1.89; 1.81]), while LogSTV(QT) (0.04 [- 1.01; 1.10]), and especially LogTT′ angle (- 0.009 [- 0.84; 0.82]) was better. Conclusion TT′ angle is a satisfactory reproducible metric of repolarization lability on the 10-second ECG.

    Original languageEnglish (US)
    Pages (from-to)708-715
    Number of pages8
    JournalJournal of Electrocardiology
    Volume47
    Issue number5
    DOIs
    StatePublished - 2014

    Fingerprint

    Electrocardiography
    Noise
    Heart Rate

    Keywords

    • ECG
    • Repolarization
    • Spatial TT′ angle

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine
    • Medicine(all)

    Cite this

    Repolarization lability measured on 10-second ECG by spatial TT′ angle : Reproducibility and agreement with QT variability. / Feeny, Albert; Han, Lichy; Tereshchenko, Larisa.

    In: Journal of Electrocardiology, Vol. 47, No. 5, 2014, p. 708-715.

    Research output: Contribution to journalArticle

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    abstract = "Background Reproducibility of spatial TT′ angle on the 10-second ECG and its agreement with QT variability has not been previously studied. Methods We analyzed 2 randomly selected 10-second segments within 3-minute resting orthogonal ECG in 172 healthy IDEAL study participants (age 38.1 ± 15.2 years, 50{\%} male, 94{\%} white). Repolarization lability was measured by the QT variance (QTV), short-term QT variability (STV(QT)), and spatial TT′ angle. Bland-Altman analysis was used to assess the agreement between different log-transformed metrics of repolarization lability, and to assess the reproducibility. Results The heart rate showed a very high reproducibility (bias 0.14{\%}, Lin's rho-c = 0.99). As expected, noise suppression by averaging improves reproducibility. Agreement between two 10-second LogQTV was poor (bias - 0.04; 95{\%} limits of agreement [- 1.89; 1.81]), while LogSTV(QT) (0.04 [- 1.01; 1.10]), and especially LogTT′ angle (- 0.009 [- 0.84; 0.82]) was better. Conclusion TT′ angle is a satisfactory reproducible metric of repolarization lability on the 10-second ECG.",
    keywords = "ECG, Repolarization, Spatial TT′ angle",
    author = "Albert Feeny and Lichy Han and Larisa Tereshchenko",
    year = "2014",
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    T1 - Repolarization lability measured on 10-second ECG by spatial TT′ angle

    T2 - Reproducibility and agreement with QT variability

    AU - Feeny, Albert

    AU - Han, Lichy

    AU - Tereshchenko, Larisa

    PY - 2014

    Y1 - 2014

    N2 - Background Reproducibility of spatial TT′ angle on the 10-second ECG and its agreement with QT variability has not been previously studied. Methods We analyzed 2 randomly selected 10-second segments within 3-minute resting orthogonal ECG in 172 healthy IDEAL study participants (age 38.1 ± 15.2 years, 50% male, 94% white). Repolarization lability was measured by the QT variance (QTV), short-term QT variability (STV(QT)), and spatial TT′ angle. Bland-Altman analysis was used to assess the agreement between different log-transformed metrics of repolarization lability, and to assess the reproducibility. Results The heart rate showed a very high reproducibility (bias 0.14%, Lin's rho-c = 0.99). As expected, noise suppression by averaging improves reproducibility. Agreement between two 10-second LogQTV was poor (bias - 0.04; 95% limits of agreement [- 1.89; 1.81]), while LogSTV(QT) (0.04 [- 1.01; 1.10]), and especially LogTT′ angle (- 0.009 [- 0.84; 0.82]) was better. Conclusion TT′ angle is a satisfactory reproducible metric of repolarization lability on the 10-second ECG.

    AB - Background Reproducibility of spatial TT′ angle on the 10-second ECG and its agreement with QT variability has not been previously studied. Methods We analyzed 2 randomly selected 10-second segments within 3-minute resting orthogonal ECG in 172 healthy IDEAL study participants (age 38.1 ± 15.2 years, 50% male, 94% white). Repolarization lability was measured by the QT variance (QTV), short-term QT variability (STV(QT)), and spatial TT′ angle. Bland-Altman analysis was used to assess the agreement between different log-transformed metrics of repolarization lability, and to assess the reproducibility. Results The heart rate showed a very high reproducibility (bias 0.14%, Lin's rho-c = 0.99). As expected, noise suppression by averaging improves reproducibility. Agreement between two 10-second LogQTV was poor (bias - 0.04; 95% limits of agreement [- 1.89; 1.81]), while LogSTV(QT) (0.04 [- 1.01; 1.10]), and especially LogTT′ angle (- 0.009 [- 0.84; 0.82]) was better. Conclusion TT′ angle is a satisfactory reproducible metric of repolarization lability on the 10-second ECG.

    KW - ECG

    KW - Repolarization

    KW - Spatial TT′ angle

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