Renal nerves, WNK4, glucocorticoids, and salt transport

David H. Ellison, Virginia L. Brooks

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations


Roles of the sympathetic nervous system versus kidney salt transporters in hypertension are debated. A study in Nature Medicine (Mu et al., 2011) shows that dietary salt excess, coupled with β-adrenergic stimulation, increases arterial pressure via glucocorticoid receptors and WNK4, suggesting interactions between these systems in the pathogenesis of hypertension.

Original languageEnglish (US)
Pages (from-to)619-620
Number of pages2
JournalCell Metabolism
Issue number6
StatePublished - Jun 8 2011

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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