Relations between fundus appearance and function: Eyes whose fellow eye has exudative age-related macular degeneration

A. Eisner, V. D. Stoumbos, M. L. Klein, S. A. Fleming

Research output: Contribution to journalArticlepeer-review

85 Scopus citations

Abstract

Foveal visual function was compared with fundus appearance for 41 eyes that had good acuity but whose fellow eye had exudative age-related macular degeneration (AMD). The visual functions tested were among those reported to be compromised by AMD. They included: (1) dark adaptation, (2) absolute sensitivity, (3) S cone-mediated sensitivity, and (4) color matching. The fundus features used to evaluate the risk of developing exudative AMD included: (1) drusen confluence, (2) drusen size, and (3) focal hyperpigmentation. For the group of eyes defined by the presence of one or more high-risk fundus characteristics, all visual functions were compromised significantly. In particular, all 21 eyes with abnormally slow rates of dark adaptation had high-risk fundi, and all 16 eyes with abnormal color matching (ie, a small effect of test area on the color match or rejection of all potential color matches) had high-risk fundi. Conversely, 30 of the 32 eyes with high-risk fundi had abnormally slow rates of dark adaptation or abnormal color matching. In addition, reduced acuity in the fellow exudative eye was associated significantly with a high-risk fundus in the nonexudative eye.

Original languageEnglish (US)
Pages (from-to)8-20
Number of pages13
JournalInvestigative Ophthalmology and Visual Science
Volume32
Issue number1
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Relations between fundus appearance and function: Eyes whose fellow eye has exudative age-related macular degeneration'. Together they form a unique fingerprint.

Cite this