TY - JOUR
T1 - Reflectance spectrophotometer
T2 - The dermatologists' sphygmomanometer for skin phototyping?
AU - Pershing, Lynn K.
AU - Tirumala, Vidyanath P.
AU - Nelson, Joel L.
AU - Corlett, Judy L.
AU - Lin, Anne G.
AU - Meyer, Laurence J.
AU - Leachman, Sancy A.
N1 - Funding Information:
This work and the familial melanoma research clinic (FMRC) were supported by development funds (LKP) and grants from NIH K23 RR17525-01, the Doris Duke Charitable Foundation (SAL), a Fellowship-To-Faculty Transition Award from the University of Utah funded in part by the Howard Hughes Medical Institute (SAL), the Huntsman Cancer Foundation for research project and database support provided to the Pedigree and Population Resource, the Tom C. Mathews, Jr Familial Melanoma Research Clinic at Huntsman Cancer Institute (SAL), the Huntsman General Clinical Research Center Public Health Service Grant (MO1 RR00064), the National Cancer Institute (NCI) Cancer Center Support Grant 5P30CA420-14, the Utah Cancer Registry, which is funded by contract no. N01-PC-35141 from the National Cancer Institute's SEER program, with additional support from the Utah Department of Health, and University of Utah. We gratefully acknowledge the willing participation of volunteers FMRC family members in this study, and thank other members of the FMRC collaborative group without whom this work would not have been possible (Scott Florell, Douglas Grossman, Glen Bowen, Ron Harris, and Larry Meyer). The information presented is part of a United States patent application US 2006/002183 A1.
PY - 2008/7
Y1 - 2008/7
N2 - To date, human skin phototype (SPT) has been determined subjectively by self- or trained investigator assessment using sun burning and/or sun tanning responses, ethnicity, hair, and eye color. This study evaluated objective reflectance spectrophotometer (RS) assessment of SPT in 353 males or females (18-72 years old with Fitzpatrick SPT I-VI) using the area-under-the-intensity curve (AUIC) over the 450-615 nm wavelength interval of reflected light (AUIC). Photoprotected constitutive skin color sites produced higher AUIC values than photo-exposed facultative skin color sites. Constitutive skin color at the upper volar arm was equal to the buttocks. Within-site and between-site AUIC reproducibility of constitutive skin color at the upper volar arm was 3 and 5% coefficient of variation (CV), respectively, which was similar to seasonal variability (8% CV). AUIC values decreased proportionately at both constitutive and facultative sites as a function of increasing SPT from I to VI (r=0.8). RS-measured constitutive skin color at the upper volar arm fit a quadratic equation (r2=0.94) that differentiated (P<0.05) between each of the six SPTs and agreed ±1 SPT category with clinician-assessed SPT. Thus, RS assessment of constitutive skin color at the upper volar arm provides a quick, noninvasive, precise, and accurate method to objectively determine SPT.
AB - To date, human skin phototype (SPT) has been determined subjectively by self- or trained investigator assessment using sun burning and/or sun tanning responses, ethnicity, hair, and eye color. This study evaluated objective reflectance spectrophotometer (RS) assessment of SPT in 353 males or females (18-72 years old with Fitzpatrick SPT I-VI) using the area-under-the-intensity curve (AUIC) over the 450-615 nm wavelength interval of reflected light (AUIC). Photoprotected constitutive skin color sites produced higher AUIC values than photo-exposed facultative skin color sites. Constitutive skin color at the upper volar arm was equal to the buttocks. Within-site and between-site AUIC reproducibility of constitutive skin color at the upper volar arm was 3 and 5% coefficient of variation (CV), respectively, which was similar to seasonal variability (8% CV). AUIC values decreased proportionately at both constitutive and facultative sites as a function of increasing SPT from I to VI (r=0.8). RS-measured constitutive skin color at the upper volar arm fit a quadratic equation (r2=0.94) that differentiated (P<0.05) between each of the six SPTs and agreed ±1 SPT category with clinician-assessed SPT. Thus, RS assessment of constitutive skin color at the upper volar arm provides a quick, noninvasive, precise, and accurate method to objectively determine SPT.
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U2 - 10.1038/sj.jid.5701238
DO - 10.1038/sj.jid.5701238
M3 - Article
C2 - 18200057
AN - SCOPUS:45349104323
SN - 0022-202X
VL - 128
SP - 1633
EP - 1640
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
IS - 7
ER -