Refinement of the arginine kinase transition-state analogue complex at 1.2 Å resolution: Mechanistic insights

Mohammad S. Yousef, Felcy Fabiola, James L. Gattis, Thayumanasamy Somasundaram, Michael S. Chapman

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

The transition-state complex of this 42 kDa homologue of creatine kinase has been refined at 1.2 Å resolution. It indicates that precise positioning of substrates and restriction of the active-site motion are important components in catalysis.

Original languageEnglish (US)
Pages (from-to)2009-2017
Number of pages9
JournalActa Crystallographica Section D: Biological Crystallography
Volume58
Issue number12
DOIs
StatePublished - Dec 1 2002

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ASJC Scopus subject areas

  • Structural Biology

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