Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

Xiang Wei; Acner Camino; Shaohua Pi; Tristan T. Hormel; William Cepurna; David Huang; John C. Morrison; Yali Jia

doi:10.1364/OL.44.001431

Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

Xiang Wei, Acner Camino, Shaohua Pi, Tristan T. Hormel, William Cepurna, David Huang, John C. Morrison, Yali Jia

Ophthalmology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercially available OCTA systems are currently based on OCT signal quality alone, without knowledge of OCTA signal quality. This results in low yield rates for further quantification. In this Letter, we developed a novel OCTA platform based on a graphics processing unit (GPU) for a real-time, high refresh rate, B-san-by-B-scan split-spectrum amplitude-decorrelation angiography. The GPU provides a real-time display of both cross-sectional and en face images to assist operators during scan acquisition and ensure OCTA scan quality.

Original language	English (US)
Pages (from-to)	1431-1434
Number of pages	4
Journal	Optics Letters
Volume	44
Issue number	6
DOIs	https://doi.org/10.1364/OL.44.001431
State	Published - 2019

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OL.44.001431

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@article{2068276a512c49e59fa46dcc3594061f,

title = "Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition",

abstract = "Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercially available OCTA systems are currently based on OCT signal quality alone, without knowledge of OCTA signal quality. This results in low yield rates for further quantification. In this Letter, we developed a novel OCTA platform based on a graphics processing unit (GPU) for a real-time, high refresh rate, B-san-by-B-scan split-spectrum amplitude-decorrelation angiography. The GPU provides a real-time display of both cross-sectional and en face images to assist operators during scan acquisition and ensure OCTA scan quality.",

author = "Xiang Wei and Acner Camino and Shaohua Pi and Hormel, {Tristan T.} and William Cepurna and David Huang and Morrison, {John C.} and Yali Jia",

note = "Funding Information: Funding. National Institutes of Health (NIH) (P30 EY010572, R01 EY010145, R01 EY023285, R01 EY024544, R01 EY027833); William and Mary Greve Special Scholar Award from Research to Prevent Blindness (RPB); Unrestricted departmental funding grant.",

year = "2019",

doi = "10.1364/OL.44.001431",

language = "English (US)",

volume = "44",

pages = "1431--1434",

journal = "Optics Letters",

issn = "0146-9592",

publisher = "The Optical Society",

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TY - JOUR

T1 - Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

AU - Wei, Xiang

AU - Camino, Acner

AU - Pi, Shaohua

AU - Hormel, Tristan T.

AU - Cepurna, William

AU - Huang, David

AU - Morrison, John C.

AU - Jia, Yali

N1 - Funding Information: Funding. National Institutes of Health (NIH) (P30 EY010572, R01 EY010145, R01 EY023285, R01 EY024544, R01 EY027833); William and Mary Greve Special Scholar Award from Research to Prevent Blindness (RPB); Unrestricted departmental funding grant.

PY - 2019

Y1 - 2019

N2 - Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercially available OCTA systems are currently based on OCT signal quality alone, without knowledge of OCTA signal quality. This results in low yield rates for further quantification. In this Letter, we developed a novel OCTA platform based on a graphics processing unit (GPU) for a real-time, high refresh rate, B-san-by-B-scan split-spectrum amplitude-decorrelation angiography. The GPU provides a real-time display of both cross-sectional and en face images to assist operators during scan acquisition and ensure OCTA scan quality.

AB - Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercially available OCTA systems are currently based on OCT signal quality alone, without knowledge of OCTA signal quality. This results in low yield rates for further quantification. In this Letter, we developed a novel OCTA platform based on a graphics processing unit (GPU) for a real-time, high refresh rate, B-san-by-B-scan split-spectrum amplitude-decorrelation angiography. The GPU provides a real-time display of both cross-sectional and en face images to assist operators during scan acquisition and ensure OCTA scan quality.

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JO - Optics Letters

JF - Optics Letters

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Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

Abstract

ASJC Scopus subject areas

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