Rapid detection of blaOXA in carbapenem-susceptible Acinetobacter radioresistens bacteremia leading to unnecessary antimicrobial administration

Adam C. Brady, James S. Lewis, Christopher Pfeiffer

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Rapid molecular techniques to identify resistant pathogens are revolutionizing antibiotic stewardship; however, it is important to recognize the limitations of these techniques. Herein we describe two cases of bacteremia that were both initially identified by genotypic testing as carbapenem-resistant Acinetobacter spp. and subsequently identified phenotypically as carbapenem-susceptible A. radioresistens. The genotypic results prompted unnecessary broad-spectrum antibiotic use and infection control concerns.

Original languageEnglish (US)
Pages (from-to)488-489
Number of pages2
JournalDiagnostic Microbiology and Infectious Disease
Volume85
Issue number4
DOIs
StatePublished - Aug 1 2016

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Acinetobacter
Carbapenems
Bacteremia
Anti-Bacterial Agents
Infection Control

Keywords

  • Acinetobacter
  • Bacteremia
  • Carbapenemase
  • Molecular diagnostics
  • Rapid diagnostics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

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AB - Rapid molecular techniques to identify resistant pathogens are revolutionizing antibiotic stewardship; however, it is important to recognize the limitations of these techniques. Herein we describe two cases of bacteremia that were both initially identified by genotypic testing as carbapenem-resistant Acinetobacter spp. and subsequently identified phenotypically as carbapenem-susceptible A. radioresistens. The genotypic results prompted unnecessary broad-spectrum antibiotic use and infection control concerns.

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