Quantum dots: Heralding a brighter future for clinical diagnostics

Tamer M. Samir, Mai M.H. Mansour, Steven C. Kazmierczak, Hassan M.E. Azzazy

Research output: Contribution to journalReview article

37 Scopus citations

Abstract

Quantum dots (QDs) are semiconductor nanocrystals that possess unique optical properties including broad-range excitation, size-tunable narrow emission spectra and high photostability, giving them considerable value in various biomedical applications. The size and composition of QDs can be varied to obtain the desired emission properties and make them amenable to simultaneous detection of multiple targets. Furthermore, numerous surface functionalizations can be used to adapt QDs to the needed application. The successful use of QDs has been reported in the areas of in vitro diagnostics and imaging. There is also potential for multimodal applications for simultaneous imaging. Toxicity issues are still a prime concern with regards to in vivo applications on account of the toxic constituents of QDs.

Original languageEnglish (US)
Pages (from-to)1755-1769
Number of pages15
JournalNanomedicine
Volume7
Issue number11
DOIs
StatePublished - Nov 1 2012

Keywords

  • clinical diagnostics
  • fluorescence
  • imaging
  • nanocrystals
  • nanoparticles
  • quantum dots

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Materials Science(all)

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