Quantitative three-dimensional microscopy approaches with applications in breast cancer biology including measurement of genomic instability

Stephen Lockett, Carlos Ortiz Solorzano, Daniel Baggett, Koei Chin

Research output: Contribution to journalReview article

Abstract

Understanding tissue development, tissue homeostasis and what goes wrong in these processes during tumorigenesis, requires knowledge of the kinetics of multiple, molecular pathways in individual cells while cells are in their tissue context. This review outlines progress and future directions necessary in quantitative microscopy for gaining this knowledge, using the mammary gland as a model system.

Original languageEnglish (US)
Pages (from-to)383-391
Number of pages9
JournalJournal of Mammary Gland Biology and Neoplasia
Volume9
Issue number4
DOIs
StatePublished - Oct 1 2004

Keywords

  • Fluorescence microscopy
  • Genomic instability
  • Mammary gland
  • Quantitative 3D imaging

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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