Quantitative three-dimensional microscopy approaches with applications in breast cancer biology including measurement of genomic instability

Stephen Lockett, Carlos Ortiz Solorzano, Daniel Baggett, Kwang-Yung Chin

Research output: Contribution to journalArticle

Abstract

Understanding tissue development, tissue homeostasis and what goes wrong in these processes during tumorigenesis, requires knowledge of the kinetics of multiple, molecular pathways in individual cells while cells are in their tissue context. This review outlines progress and future directions necessary in quantitative microscopy for gaining this knowledge, using the mammary gland as a model system.

Original languageEnglish (US)
Pages (from-to)383-391
Number of pages9
JournalJournal of Mammary Gland Biology and Neoplasia
Volume9
Issue number4
DOIs
StatePublished - Oct 2004
Externally publishedYes

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Genomic Instability
Microscopy
Breast Neoplasms
Human Mammary Glands
Carcinogenesis
Homeostasis

Keywords

  • Fluorescence microscopy
  • Genomic instability
  • Mammary gland
  • Quantitative 3D imaging

ASJC Scopus subject areas

  • Cancer Research

Cite this

Quantitative three-dimensional microscopy approaches with applications in breast cancer biology including measurement of genomic instability. / Lockett, Stephen; Solorzano, Carlos Ortiz; Baggett, Daniel; Chin, Kwang-Yung.

In: Journal of Mammary Gland Biology and Neoplasia, Vol. 9, No. 4, 10.2004, p. 383-391.

Research output: Contribution to journalArticle

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