Protein A-coated erythrocyte binding to cell surface antigens: Application to quantitate retrovirus infectivity in vitro

Thomas Fitting, David Kabat

Research output: Contribution to journalArticle

Abstract

Fibroblasts infected with murine leukemia virus (MuLV) bind erythrocytes coated with protein A to form rosettes in the presence of MuLV-specific antisera. This method, which is potentially applicable to any retrovirus and susceptible cell, has been specifically adapted as a focus assay for quantitating both ecotropic and xenotropic MuLV.

Original languageEnglish (US)
Pages (from-to)653-655
Number of pages3
JournalVirology
Volume111
Issue number2
DOIs
StatePublished - Jun 1981

ASJC Scopus subject areas

  • Virology

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