Abstract
Background: Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. Failures are a reality of surgery; to limit failures, we must first understand and quantify them.Purpose: The purposes of this study were to determine the rate and factors associated with graft failure after anatomic ACL reconstruction performed with allograft.Study design: Case series; Level of evidence, 4.Methods: All consecutive subjects who underwent anatomic single- or double-bundle ACL reconstruction with allograft between January 2007 and December 2009 were included and followed clinically. Graft failure was defined as patient-reported instability, pathological laxity during the physical examination, or evidence of a failed graft on magnetic resonance imaging or during arthroscopy. Potential predictors of graft failure that were explored included subject age, sex, height, weight, body mass index, meniscus injury, and time of return to preinjury sports.Results: There were 206 subjects included in this study: 168 double-bundle and 38 single-bundle reconstructions. Overall, 27 (13%) subjects experienced graft failure. Twenty-three (13%) double-bundle subjects failed. The characteristics associated with double-bundle graft failure were younger age (19 vs 25 years, P <.001) and earlier return to sports (at 222 vs 267 days, P =.007). Four (11%) of the single-bundle subjects failed. The characteristics associated with single-bundle graft failure were younger age (19 vs 24 years, P =.049) and increased body mass (83 vs 65 kg, P =.031).Conclusion: The overall graft failure rate after anatomic ACL reconstruction with allograft was 13%. Younger age, earlier return to sports, and a higher body weight were associated with graft failure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 800-807 |
| Number of pages | 8 |
| Journal | American Journal of Sports Medicine |
| Volume | 40 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2012 |
| Externally published | Yes |
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Keywords
- allograft
- anatomic
- anterior cruciate ligament (ACL)
- failure rate
ASJC Scopus subject areas
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation
- Medicine(all)
Cite this
Prospective analysis of failure rate and predictors of failure after anatomic anterior cruciate ligament reconstruction with allograft. / Van Eck, Carola F.; Schkrohowsky, Joshua G.; Working, Zachary; Irrgang, James J.; Fu, Freddie H.
In: American Journal of Sports Medicine, Vol. 40, No. 4, 01.04.2012, p. 800-807.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Prospective analysis of failure rate and predictors of failure after anatomic anterior cruciate ligament reconstruction with allograft
AU - Van Eck, Carola F.
AU - Schkrohowsky, Joshua G.
AU - Working, Zachary
AU - Irrgang, James J.
AU - Fu, Freddie H.
PY - 2012/4/1
Y1 - 2012/4/1
N2 - Background: Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. Failures are a reality of surgery; to limit failures, we must first understand and quantify them.Purpose: The purposes of this study were to determine the rate and factors associated with graft failure after anatomic ACL reconstruction performed with allograft.Study design: Case series; Level of evidence, 4.Methods: All consecutive subjects who underwent anatomic single- or double-bundle ACL reconstruction with allograft between January 2007 and December 2009 were included and followed clinically. Graft failure was defined as patient-reported instability, pathological laxity during the physical examination, or evidence of a failed graft on magnetic resonance imaging or during arthroscopy. Potential predictors of graft failure that were explored included subject age, sex, height, weight, body mass index, meniscus injury, and time of return to preinjury sports.Results: There were 206 subjects included in this study: 168 double-bundle and 38 single-bundle reconstructions. Overall, 27 (13%) subjects experienced graft failure. Twenty-three (13%) double-bundle subjects failed. The characteristics associated with double-bundle graft failure were younger age (19 vs 25 years, P <.001) and earlier return to sports (at 222 vs 267 days, P =.007). Four (11%) of the single-bundle subjects failed. The characteristics associated with single-bundle graft failure were younger age (19 vs 24 years, P =.049) and increased body mass (83 vs 65 kg, P =.031).Conclusion: The overall graft failure rate after anatomic ACL reconstruction with allograft was 13%. Younger age, earlier return to sports, and a higher body weight were associated with graft failure.
AB - Background: Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. Failures are a reality of surgery; to limit failures, we must first understand and quantify them.Purpose: The purposes of this study were to determine the rate and factors associated with graft failure after anatomic ACL reconstruction performed with allograft.Study design: Case series; Level of evidence, 4.Methods: All consecutive subjects who underwent anatomic single- or double-bundle ACL reconstruction with allograft between January 2007 and December 2009 were included and followed clinically. Graft failure was defined as patient-reported instability, pathological laxity during the physical examination, or evidence of a failed graft on magnetic resonance imaging or during arthroscopy. Potential predictors of graft failure that were explored included subject age, sex, height, weight, body mass index, meniscus injury, and time of return to preinjury sports.Results: There were 206 subjects included in this study: 168 double-bundle and 38 single-bundle reconstructions. Overall, 27 (13%) subjects experienced graft failure. Twenty-three (13%) double-bundle subjects failed. The characteristics associated with double-bundle graft failure were younger age (19 vs 25 years, P <.001) and earlier return to sports (at 222 vs 267 days, P =.007). Four (11%) of the single-bundle subjects failed. The characteristics associated with single-bundle graft failure were younger age (19 vs 24 years, P =.049) and increased body mass (83 vs 65 kg, P =.031).Conclusion: The overall graft failure rate after anatomic ACL reconstruction with allograft was 13%. Younger age, earlier return to sports, and a higher body weight were associated with graft failure.
KW - allograft
KW - anatomic
KW - anterior cruciate ligament (ACL)
KW - failure rate
UR - http://www.scopus.com/inward/record.url?scp=84859498091&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859498091&partnerID=8YFLogxK
U2 - 10.1177/0363546511432545
DO - 10.1177/0363546511432545
M3 - Review article
C2 - 22238055
AN - SCOPUS:84859498091
VL - 40
SP - 800
EP - 807
JO - American Journal of Sports Medicine
JF - American Journal of Sports Medicine
SN - 0363-5465
IS - 4
ER -