Progressive Dilation of the Ascending Aorta in Children With Isolated Bicuspid Aortic Valve

Kathryn Holmes, Christoph U. Lehmann, Darshan Dalal, Khuram Nasir, Harry C. Dietz, William J. Ravekes, W. Reid Thompson, Philip J. Spevak

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Although patients with bicuspid aortic valves (BAVs) are predisposed to ascending aortic (AA) dilation, stenosis, and dissection, the development of aortic disease in children with BAVs is poorly described. The purposes of this study were to determine the rate of change of AA diameter in children with BAVs and to identify risk factors for the development of aortic dilation. The echocardiograms of 276 children aged 4), and 70 (25%) were moderately abnormal (z between 2 and 4). The mean ± SD AA diameter increased more than expected, at a rate of 0.18 ± 0.30 z score per year (p 2, at follow-up. Univariate analysis demonstrated right-noncoronary commissural fusion (p

Original languageEnglish (US)
Pages (from-to)978-983
Number of pages6
JournalAmerican Journal of Cardiology
Volume99
Issue number7
DOIs
StatePublished - Apr 1 2007
Externally publishedYes

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Aorta
Dilatation
Aortic Diseases
Aortic Valve Stenosis
Dissection
Bicuspid Aortic Valve

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Progressive Dilation of the Ascending Aorta in Children With Isolated Bicuspid Aortic Valve. / Holmes, Kathryn; Lehmann, Christoph U.; Dalal, Darshan; Nasir, Khuram; Dietz, Harry C.; Ravekes, William J.; Thompson, W. Reid; Spevak, Philip J.

In: American Journal of Cardiology, Vol. 99, No. 7, 01.04.2007, p. 978-983.

Research output: Contribution to journalArticle

Holmes, K, Lehmann, CU, Dalal, D, Nasir, K, Dietz, HC, Ravekes, WJ, Thompson, WR & Spevak, PJ 2007, 'Progressive Dilation of the Ascending Aorta in Children With Isolated Bicuspid Aortic Valve', American Journal of Cardiology, vol. 99, no. 7, pp. 978-983. https://doi.org/10.1016/j.amjcard.2006.10.065
Holmes, Kathryn ; Lehmann, Christoph U. ; Dalal, Darshan ; Nasir, Khuram ; Dietz, Harry C. ; Ravekes, William J. ; Thompson, W. Reid ; Spevak, Philip J. / Progressive Dilation of the Ascending Aorta in Children With Isolated Bicuspid Aortic Valve. In: American Journal of Cardiology. 2007 ; Vol. 99, No. 7. pp. 978-983.
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