Preservation of 32 human kidneys by simple cold storage for more than 48 hours

J. M. Barry, T. R. Hefty, T. R. Hatch, E. F. Fuchs, E. S. Tank

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Abstract

Transplant centers are reluctant to use kidneys stored cold for more than 48 hours. During a 6-year interval we transplanted 32 kidneys preserved by intracellular electrolyte flushing that were stored cold for 48.2 to 61.4 hours. Of the recipients 91 per cent required dialysis within 1 week after transplantation. The mean serum creatinine nadir within 1 month was 3.0 mg. per dl. and graft survival at 1 month was 81 per cent. Short-term kidney graft function was not influenced significantly by the addition of magnesium sulfate to the flush solutions or by cyclosporin immunosuppression. The 1 and 2-year actuarial kidney graft survival rates were 72 and 58 per cent, respectively. The 1 and 2-year mean serum creatinine levels were 1.9 and 1.6 mg. per dl., respectively. Kidneys can be transplanted successfully after 48 hours of simple cold storage following flushing with an ice-cold intracellular electrolyte solution.

Original languageEnglish (US)
Pages (from-to)195-196
Number of pages2
JournalJournal of Urology
Volume137
Issue number2
DOIs
StatePublished - Jan 1 1987

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ASJC Scopus subject areas

  • Urology

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