Preservation of 32 human kidneys by simple cold storage for more than 48 hours

John Barry, T. R. Hefty, T. R. Hatch, Eugene Fuchs, E. S. Tank

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Transplant centers are reluctant to use kidneys stored cold for more than 48 hours. During a 6-year interval we transplanted 32 kidneys preserved by intracellular electrolyte flushing that were stored cold for 48.2 to 61.4 hours. Of the recipients 91 per cent required dialysis within 1 week after transplantation. The mean serum creatinine nadir within 1 month was 3.0 mg. per dl. and graft survival at 1 month was 81 per cent. Short-term kidney graft function was not influenced significantly by the addition of magnesium sulfate to the flush solutions or by cyclosporin immunosuppression. The 1 and 2-year actuarial kidney graft survival rates were 72 and 58 per cent, respectively. The 1 and 2-year mean serum creatinine levels were 1.9 and 1.6 mg. per dl., respectively. Kidneys can be transplanted successfully after 48 hours of simple cold storage following flushing with an ice-cold intracellular electrolyte solution.

Original languageEnglish (US)
Pages (from-to)195-196
Number of pages2
JournalJournal of Urology
Volume137
Issue number2
StatePublished - 1987

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Kidney
Graft Survival
Electrolytes
Creatinine
Transplants
Magnesium Sulfate
Ice
Serum
Immunosuppression
Cyclosporine
Dialysis
Transplantation

ASJC Scopus subject areas

  • Urology

Cite this

Preservation of 32 human kidneys by simple cold storage for more than 48 hours. / Barry, John; Hefty, T. R.; Hatch, T. R.; Fuchs, Eugene; Tank, E. S.

In: Journal of Urology, Vol. 137, No. 2, 1987, p. 195-196.

Research output: Contribution to journalArticle

Barry, John ; Hefty, T. R. ; Hatch, T. R. ; Fuchs, Eugene ; Tank, E. S. / Preservation of 32 human kidneys by simple cold storage for more than 48 hours. In: Journal of Urology. 1987 ; Vol. 137, No. 2. pp. 195-196.
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