Pregnancy attenuates activity of the baroreceptor reflex

Virginia Brooks, R. R. Quesnell, S. R. Cumbee, V. S. Bishop

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

1. Pregnancy-induced changes in acute blood pressure regulation are reviewed. 2. Pregnant animals are less able to maintain arterial pressure during haemorrhage than non-pregnant animals. 3. Baroreceptor reflex-mediated increases in heart rate, renal sympathetic activity, vasopressin, ACTH and cortisol are reduced during pregnancy. Therefore, one explanation for the subnormal ability of pregnant animals to regulate arterial pressure during haemorrhage is that the baroreceptor reflex is not as effective. 4. Chronic increases in oestrogen levels in non-pregnant rabbits do not reduce the gain of baroreflex control of renal E sympathetic activity. This and other findings suggest that oestrogen alone does not mediate the blunted baroreflex activity observed during pregnancy.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalClinical and Experimental Pharmacology and Physiology
Volume22
Issue number2
StatePublished - 1995

Fingerprint

Baroreflex
Pregnancy
Arterial Pressure
Estrogens
Hemorrhage
Kidney
Vasopressins
Adrenocorticotropic Hormone
Hydrocortisone
Heart Rate
Rabbits
Blood Pressure

Keywords

  • ACTH
  • Arterial pressure
  • Baroreflex
  • Cortisol
  • Dogs
  • Haemorrhage
  • Heart rate
  • Oestrogen
  • Rabbits
  • Sympathetic nervous system
  • Vasopressin

ASJC Scopus subject areas

  • Physiology
  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Pregnancy attenuates activity of the baroreceptor reflex. / Brooks, Virginia; Quesnell, R. R.; Cumbee, S. R.; Bishop, V. S.

In: Clinical and Experimental Pharmacology and Physiology, Vol. 22, No. 2, 1995, p. 152-156.

Research output: Contribution to journalArticle

Brooks, V, Quesnell, RR, Cumbee, SR & Bishop, VS 1995, 'Pregnancy attenuates activity of the baroreceptor reflex', Clinical and Experimental Pharmacology and Physiology, vol. 22, no. 2, pp. 152-156.
Brooks, Virginia ; Quesnell, R. R. ; Cumbee, S. R. ; Bishop, V. S. / Pregnancy attenuates activity of the baroreceptor reflex. In: Clinical and Experimental Pharmacology and Physiology. 1995 ; Vol. 22, No. 2. pp. 152-156.
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