TY - JOUR
T1 - Predictive value of obstructive sleep apnoea assessed by the Berlin Questionnaire for outcomes after the catheter ablation of atrial fibrillation
AU - Chilukuri, Karuna
AU - Dalal, Darshan
AU - Marine, Joseph E.
AU - Scherr, Daniel
AU - Henrikson, Charles A.
AU - Cheng, Alan
AU - Nazarian, Saman
AU - Spragg, David
AU - Berger, Ronald
AU - Calkins, Hugh
PY - 2009/7/1
Y1 - 2009/7/1
N2 - AimsObstructive sleep apnoea (OSA) is a risk factor for atrial fibrillation (AF) recurrence after catheter ablation. The purpose of this study is to determine whether OSA assessed by the simple tool, the Berlin Questionnaire (BQ), is useful in predicting the efficacy of catheter ablation of AF.Methods and resultsThe patient population consisted of 210 consecutive patients [mean age 58 ± 10 years, 167 (80) male, 119 (57) paroxysmal] who underwent catheter ablation of AF and completed the BQ. Clinical success was defined as at least 90 reduction in AF burden after 3-month blanking period. Mean duration of follow-up was 25 ± 12 months. One hundred and one of the 118 (85) patients at low risk for OSA had clinical success as opposed to 64 of the 92 (70) patients at high risk for OSA on BQ (P = 0.005). On multivariate analysis, only high-risk for OSA on BQ emerged as an independent predictor of procedural failure (OR 4.53, CI: 1.21-16.87, P = 0.02).ConclusionHigh risk of OSA on BQ predicts procedural failure after catheter ablation of AF. We recommend the use of BQ for risk-stratifying patients for OSA prior to AF ablation procedures and to identify patients for formal sleep study assessment.
AB - AimsObstructive sleep apnoea (OSA) is a risk factor for atrial fibrillation (AF) recurrence after catheter ablation. The purpose of this study is to determine whether OSA assessed by the simple tool, the Berlin Questionnaire (BQ), is useful in predicting the efficacy of catheter ablation of AF.Methods and resultsThe patient population consisted of 210 consecutive patients [mean age 58 ± 10 years, 167 (80) male, 119 (57) paroxysmal] who underwent catheter ablation of AF and completed the BQ. Clinical success was defined as at least 90 reduction in AF burden after 3-month blanking period. Mean duration of follow-up was 25 ± 12 months. One hundred and one of the 118 (85) patients at low risk for OSA had clinical success as opposed to 64 of the 92 (70) patients at high risk for OSA on BQ (P = 0.005). On multivariate analysis, only high-risk for OSA on BQ emerged as an independent predictor of procedural failure (OR 4.53, CI: 1.21-16.87, P = 0.02).ConclusionHigh risk of OSA on BQ predicts procedural failure after catheter ablation of AF. We recommend the use of BQ for risk-stratifying patients for OSA prior to AF ablation procedures and to identify patients for formal sleep study assessment.
KW - Atrial fibrillation
KW - Berlin Questionnaire
KW - Catheter ablation
KW - Efficacy
KW - Sleep apnoea
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U2 - 10.1093/europace/eup064
DO - 10.1093/europace/eup064
M3 - Article
C2 - 19297363
AN - SCOPUS:67650869761
VL - 11
SP - 896
EP - 901
JO - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
JF - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
SN - 1099-5129
IS - 7
ER -